Hypertension and Vascular Research Center

Volume 3 Issue 3

Rachel W. Reynolds — Tue, 10 Nov 2009 16:15:34 GMT

Newsletter, Volume 3 Issue 3, hypertension, vascular research

Lorna G Moore

Rachel W. Reynolds — Tue, 03 Nov 2009 20:17:46 GMT

Lorna G Moore. Pregnancy. greatest physiological challenges. human lifespan. basic physiological processes. high attitude. chronic hypoxia. Effects of pregnancy. Vessel diameter. decreasing DNA synthesis.

New Protocol Information Request Form(2)

Rachel W. Reynolds — Thu, 29 Oct 2009 14:41:51 GMT

New Protocol Information Request Form. Assays. Samples. Projects. Investigator.

Volume 1 Issue 1

Rachel W. Reynolds — Tue, 29 Sep 2009 14:27:34 GMT

Page 1 Hypertension In The News Page 1 Hypertension In The News Page 1 Hypertension & Vascular Disease has been elevated from a program to one of eleven institutional recognized research centers. It will now report directly to the Deans Office. A welcome change that has been a long time coming according to Carlos Ferra

Volume 2 Issue 1

Rachel W. Reynolds — Tue, 29 Sep 2009 14:26:03 GMT

` Each year, the Division of Surgical Sciences hosts a Residents and Fellows Research Day, an event which highlights the extensive research and training efforts by Division. Sixteen fellows and students from the Hypertension Center participated in the 15th Annual Residents and Fellows Research Day held November 15, 200

Volume 2 Issue 2

Rachel W. Reynolds — Tue, 29 Sep 2009 13:36:11 GMT

K. Bridget Brosnihan, Ph.D., a professor in the Hypertension and Vascular Research Center of Wake Forest University Baptist Medical Center, has received the Page-Bradley Lifetime Achievement Award from the American Heart Associations Council for High Blood Pressure Research. The award is named in honor of Irvine Page a

Volume 3 Issue 1

Rachel W. Reynolds — Tue, 29 Sep 2009 13:33:37 GMT

`As many of you are aware, Carlos M. Ferrario, M.D., has stepped down after serving our medical school with distinction as founder and director of the Hypertension & Vascular Research Center since 1992. He will continue as a professor in the division of surgical sciences and department of physiology and pharmacology. D

Volume 3 Issue 2

Rachel W. Reynolds — Tue, 29 Sep 2009 13:30:21 GMT

`K. Bridget Brosnihan, Ph.D., a professor in the Hypertension and Vascular Research Center of Wake Forest University Baptist Medical Center, received an honorary degree from the College of Saint Mary in Omaha, Neb., on May 18. “Dr. Brosnihans scientific achievements as an independent and pathfinder investigator have re

COSEHC

Rachel W. Reynolds — Wed, 23 Sep 2009 14:10:15 GMT

The Consortium for Southeastern Hypertension Control (COSEHC) is a professional organization of physicians, scientists, and health care providers working together to reduce the incidence of high blood pressure and hypertension-related cardiovascular disease outcomes (heart attacks, strokes, renal disease and heart failure) in the southeastern region of the United States.

New Protocol Information Request

Rachel W. Reynolds — Wed, 23 Sep 2009 13:45:50 GMT

S:\HYP\HYPER\USERS\RREYNOLDS\Website\Word Documents\Research Laboratories\New Protocol Data Sheet 5-25-07.doc Hypertension Core Lab Part of The Hypertension and Vascular Research Center Medical Center Blvd. Winston-Salem, NC 27157-1032 (336) 716-3553 Fax: (336) 716-2295Laboratory Contact: Louise Campbell Phone: (336) 7

Request for Analyses

Rachel W. Reynolds — Wed, 23 Sep 2009 13:43:56 GMT

REQUEST FOR ANALYSES BY HYPERTENSION CORE LABORATORY RESEARCH SAMPLES ONLY -PLEASE FILL OUT ONE SHEET FOR EACH SET OF SAMPLES Primary Investigator________________________PHONE #:______________DATE:____________ Secondary Investigator_______________________________ GRANT/ACCOUNT NUMBER Billing Information STUDY NAME_____

Core Lab Assays

Ektron TestUser — Mon, 24 Aug 2009 16:29:37 GMT

Core Lab Assays

Core Laboratory Links

Rachel W. Reynolds — Wed, 21 Oct 2009 17:42:11 GMT

Core Laboratory Links

Endocrine-Collaborators

Ektron TestUser — Fri, 21 Aug 2009 16:18:46 GMT

Endocrine-Collaborators

Faculty and Staff

Mark Flaherty — Sat, 26 Sep 2009 15:03:28 GMT

The Hypertension and Vascular Research Center - Faculty & Staff

Newsletters

Rachel W. Reynolds — Tue, 10 Nov 2009 16:18:43 GMT

Hypertension and Vascular Research Center Newsletters

Seminars

Rachel W. Reynolds — Wed, 16 Sep 2009 17:39:58 GMT

A listing of the Hypertension and Vascular Research Center Seminar Series.

Transgenic Rat Facility

Rachel W. Reynolds — Thu, 17 Sep 2009 14:35:10 GMT

The Transgenic Rat Facility provides investigators at the Wake Forest University School of Medicine and other research facilities with transgenic (TG) rats having genetic alterations of the renin-angiotensin system. At present the Transgenic Rat Facility has breeding colonies for three different transgenic rats. In one of these the mouse renin-2 gene (mRen2) has been incorporated into the rat genome.

Molecular and Cell Biology Core Lab

Rachel W. Reynolds — Thu, 17 Sep 2009 14:33:53 GMT

The Molecular and Cell Biology Core facilitates the use of state-of-the-art cellular and molecular biology technologies for investigators within the Hypertension & Vascular Disease Center as well as national and international scientists on a fee for service basis. The Molecular Biology unit provides reagents and expertise for a variety of technologies, including, but not limited to, real time-polymerase chain reaction, reverse transcriptase-polymerase chain reaction, gene array hybridization, yeast and bacterial two-hybrid analysis, Northern, Southern and Western blot hybridization, development of antisense oligonucleotides and siRNAs, generation of recombinant adenoviral constructs, subcloning, riboprobe development, and promoter analysis.

Hypertension Core Laboratory

Rachel W. Reynolds — Thu, 29 Oct 2009 15:04:23 GMT

The Hypertension and Vascular Research Center Core Laboratory performs radioimmunoassays (RIAs) and enzyme-immunoassay (EIAs), and enzymatic assays for clinical and research purposes. The laboratory is CLIA (Clinical Laboratory Improvement Amendment)-certified and has demonstrated proficiency in immunoassays. We have participated in NIH-funded, FDA-approved testing and drug-company-sponsored projects. We offer competitive prices customized to meet your research needs. Please check our list of assays for more information or contact us directly.

Pharmacology of Hypertension

Rachel W. Reynolds — Thu, 17 Sep 2009 15:12:53 GMT

The objective of my laboratory is to investigate the mechanistic relation between the brain and kidney in the long-term control of arterial pressure and body fluid volume. Our lab explores the normal function of specific peptidergic systems that interact with cardiovascular reflex areas of the brain by examining actions of peptide transmitters at specific brain sites and by assessing neurotransmitter release.

Pathobiology of Vascular Disease

Rachel W. Reynolds — Thu, 17 Sep 2009 15:08:53 GMT

Dr. Strawn’s laboratory investigates the role of the renin-angiotensin system in the development of cells that participate in atherogenesis and hypertension-related vascular remodeling. Recent studies from his laboratory identified a bone marrow renin-angiotensin system that may regulate hematopoiesis and the generation of blood-borne immune cells.

Hypertension Cell and Molecular Biology Laboratory

Rachel W. Reynolds — Thu, 17 Sep 2009 15:07:26 GMT

Research in the Tallant/Gallagher laboratory focuses on the cellular and molecular regulation of the renin-angiotensin system (RAS). Studies are designed to examine the role of the RAS in a variety of complex, chronic pathologies, including hypertension, diabetes, and atherosclerosis.

Physiology of Hypertension

Rachel W. Reynolds — Mon, 28 Sep 2009 16:33:50 GMT

The primary goal of my laboratory is to define the peripheral vascular, cardiac, and central neural mechanisms through which the renin angiotensin system contributes to the regulation of blood pressure. How these mechanisms are altered in the development and maintenance of high blood pressure is of particular interest. One component of my laboratory studies the hemodynamic mechanisms responsible for the cardiovascular actions of the renin angiotensin system. We have sought to define the receptors subtypes at which various angiotensin peptides affect blood pressure. In the course of trying to achieve this objective I have utilized a variety of preparations.

Laboratory of Endocrine Aspects of Hypertension

Rachel W. Reynolds — Wed, 21 Oct 2009 18:33:53 GMT

One important aspect of the pathogenesis of hypertension concerns the understanding of the role of hormones in the control of blood pressure and vascular reactivity. Research approaches in our laboratory entail understanding the contribution of the renin angiotensin system to pregnancy induced hypertension. In addition, our laboratory is interested in the cardiovascular protective role of estrogen and its interaction with the renin-angiotensin system. The laboratory uses pharmacologic and physiologic techniques to study vascular reactivity, biochemical methods to measure tissue levels of neuroendocrine hormones, and molecular techniques to study the regulation of the key proteins.

Center for Excellence in Hypertension and Vascular Disease

Rachel W. Reynolds — Thu, 17 Sep 2009 15:04:47 GMT

Basic research in the Hypertension and Vascular Research Center seeks to advance understanding of disease processes at the organ level. Our research on the molecular and biochemical physiology of the renin angiotensin system (RAS) and vasodilator hormones complements our investigation of the mechanisms responsible for the development of high blood pressure and atherosclerosis in humans.

Biochemistry of Hypertension and Organ Injury

Rachel W. Reynolds — Thu, 17 Sep 2009 14:53:57 GMT

The long-term objective of the laboratory is to elucidate the role of the kidney and the renin-angiotensin system (RAS) in the regulation of blood pressure and renal injury. Our current studies also focus on gender differences regarding the relationship of the RAS to hypertension, tissue injury and salt-sensitivty.

QR - Hypertension and Vascular Research Center

Jan Eric Strohl — Mon, 14 Sep 2009 14:51:49 GMT

QR Hypertension and Vascular Research CenterHyertension and Vascular Research CenterPhone3367165819Fax3367166644The Hypertension and Vascular Research CenterWake Forest University School of MedicineWinston SalemNC27157Department of Research

Research Labs

Star Lee — Thu, 29 Oct 2009 13:27:06 GMT

A listing of Research and Core Laboratories in the Hypertension and Vascular Research Center.

Hypertension and Vascular Research Center

Rachel W. Reynolds — Wed, 16 Sep 2009 17:26:03 GMT

The Hypertension Center was established in 1992 under the direction of Drs. Carlos Ferrario and Richard Dean within the Division of Surgical Sciences to integrate basic science and clinical efforts for advancements leading to the prevention and treatment of high blood pressure and vascular disease. In 2007, The Hypertension and Vascular Research Center achieved institutional center status.