|
The Section of Radiation Biology is one of the three divisions of the Department of Radiation Oncology, Wake Forest University School of Medicine.
Mission Statement
- To utilize interdisciplinary advances in cell and molecular biology and translational research to develop novel therapeutic approaches that will enhance our ability to prevent and treat cancer
- To educate graduate students, post-doctoral fellows and radiation oncology residents in the principles and proper conduct of basic research
- To provide leadership and service to the Department of Radiation Oncology, the Comprehensive Cancer Center of Wake Forest University Health Sciences, and the University for the advancement of cancer and radiation biology research
Organization
Faculty
Mike Robbins, PhD Professor and Section Head
William Blackstock, MD Associate Professor
Hannah Caldas, PhD Assistant Professor
Waldemar Debinski, MD, PhD Professor and Director, Brain Tumor Center of Excellence
Linda J. Metheny-Barlow, PhD Assistant Professor
Weiling Zhao, PhD Assistant Professor
Administrative Personnel
Darlene Cantrell, Secretary
- (Tel) 336-713-7638
- (Fax) 336-713-7639
Selected Publications
Zhao, W., O'Malley, Y., Wei, S., and Robbins M.E.C., Irradiation of rat tubule epithelial cells alters the expression of gene products associated with the synthesis and degradation of extracellular matrix. Int J Radiat Biol,76, 391-402, 2000.
Ying Zhang, Weiling Zhao, Hannah J. Zhang, Frederick E. Doman, and Larry W. Oberley: Overexpression of copper zinc superoxide dismutase suppresses human glioma cell growth. Cancer Res, 62:1205-1212, 2002.
Zhang HJ, Zhao W, Venkataraman S, Robbins ME, Buettner GR, Kregel KC, Oberley LW:Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species. J Biol Chem. 277(23):20919-26, 2002.
Ramljak, D., Romanczyk, L.J., Metheny-Barlow, L.J., Thompson, N., Knezevic, V., Galperin, M., Ramesh, A. and Dickson, R.B.: Pentameric procyanidin from Theobromo cacao selectively inhibits growth of human breast cancer cells. Mol Cancer Ther, 4, 537-546, 2005.
Li, L.Y., Barlow, K.D. and Metheny-Barlow, L.J.: Angiopoietins and Tie2 in health and disease. Pediatric Endocrin Rev, 3, 399-408, 2005.
Brown, W.R., Thore, C.R. Moody, D.M., Robbins, M.E.C. and Wheeler, K.T. Vascular damage after fractionated whole brain irradiation in rats. Radiat. Res.164; 662-668, (2005).
Robbins, M.E. and Diz, D.I. Pathogenic role of the renin-angiotensin system (RAS) in modulating radiation-induced late effects. Int J. Radiat. Oncol. Biol. Phys. 64; 6-12, (2006).
Shaw EG and Robbins ME. The management of radiation-induced brain injury. Cancer Treat Res 128, 7-22 (2006).
Shaw, E.G., Rosdahl, R., D’Agostino, R.B. Jr., Lovato, M., Naughton, M., Robbins, M.E. and Rapp, S.R. A phase II study of donepezil in irradiated brain tumor patients: effect on cognitive function, mood, and quality of life. J Clin Oncol:24, 1415-1420, (2006).
Metheny-Barlow, L.J. and Li, L.Y. Vascular Endothelial Growth Inhibitor (VEGI), an endogenous negative regulator of angiogenesis. Semin Ophthalmol, 21, 49-58, 2006.
Invited External Speakers
Seminar Program
Journal Club Schedule
Links
Department of Cancer Biology, WFUSM
WFU Comprehensive Cancer Center
Radiation Research Society
American Association for Cancer Research
American Cancer Society
International Union Against Cancer (UICC)
Radiological Society of North America (RSNA)
Society for Free Radical Biology and Medicine |