Education: 
University of Buenos Aires School of Medicine, Argentina, M.D. (1978)
University of Buenos Aires School of Medicine, Argentina, Ph.D. (1986)

Research Area:
Aging of the Neuromuscular System

Academic Activities:
Member of the NIH Skeletal Muscle Biology NIH Study Section (2001-2004)
Member of the NIH Skeletal Muscle Biology and Exercise Physiology Study
Section (2003-2007)
Member of the Internal Review Board (IRB) 1995-present

Activities in Medical & Graduate Education:
Teaching and training graduate and undergraduate students.
Teaching and training medical students and medical residents.
Lectures in Physiology and Pharmacology, Cell Biology and Clinical Neuroscience.

Brief Summary of Research:
Structural and functional alterations in the neuromuscular system lead to physical disability and loss of independence with aging. Despite the importance of muscle strength in preventing physical disability, the cellular and molecular mechanisms responsible for the age-dependent decline in the neuromuscular system are only partially understood. The main focus of our research is to determine the molecular and cellular mechanisms underlying the age-dependent alterations in structure and function of motor neurons and skeletal muscle fibers.  Particularly, we are interested in the reciprocal interaction between muscle cells and spinal cord motor neurons, the role of trophic factors and ion channels in tissue function, and interventions aimed at ameliorating and/or delaying the age-dependent impairment in the neuromuscular system.