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David W. Busija, Ph.D.

David W. Busija, Ph.D.

Professor, Physiology and Pharmacology
Contact Information
Office:
336-716-4355
Fax:
336-716-0504
Education & Training
  BSUniversity of Pittsburgh1972
  MAUniversity of Kansas1974
  PhDUniversity of Kansas1978
Memberships
American Physiological Society
Aha - Stroke Council
David W. Busija, Ph.D.

David W. Busija, Ph.D.

Professor, Physiology and Pharmacology
Contact Information
Office:
336-716-4355
Fax:
336-716-0504
Research Interests
diabetes, neurosciences/behavior, animals, cells/membranes/tissu, animals, whole, cardiovascular system, molecular biology/molecular me, vascular diseases, nervous/sensory system/behavio, basic mechanisms
Recent Publications
Mitochondrial nitric oxide synthase: current concepts and controversies, Front Biosci, 11/06/2009

Immediate neuronal preconditioning by NS1619, Brain Res, 10/20/2009

PACAP and VIP differentially preserve neurovascular reactivity after global cerebral ischemia in newborn pigs, Brain Res, 09/10/2009

Neuroprotective effect of adenoviral catalase gene transfer in cortical neuronal cultures, Brain Res, 07/27/2009

Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance, Am J Physiol Regul Integr Comp Physiol, 04/28/2009

Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivation in cultured cortical neurons, Am J Physiol Cell Physiol, 04/20/2009

Acute treatment with rosuvastatin protects insulin resistant (C57BL/6J ob/ob) mice against transient cerebral ischemia, J Cereb Blood Flow Metab, 03/10/2009

The cerebrovascular endothelium: a target for neuroprotection [abstract], Biomed Pharmacother, 02/06/2009

Cerebromicrovascular endothelial cells are resistant to L-glutamate, Am J Physiol Regul Integr Comp Physiol, 01/28/2009

Mechanisms involved in the cerebrovascular dilator effects of cortical spreading depression, Prog Neurobiol, 12/16/2008

Mitochondrial-mediated suppression of ROS production upon exposure of neurons to lethal stress: mitochondrial targeted preconditioning, Adv Drug Deliv Rev, 11/04/2008

ROS-independent preconditioning in neurons via activation of mitoKATP channels by BMS-191095, J Cereb Blood Flow Metab, 07/22/2008

Delayed neuronal preconditioning by NS1619 is independent of calcium activated potassium channels, J Neurochem, 06/12/2008

A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice, Biol Reprod, 06/02/2008

Acetazolamide induces indomethacin and ischaemia-sensitive pial arteriolar vasodilation in the piglet, Acta Paediatrica, 03/31/2008

Mechanisms involved in the cerebrovascular dilator effects of N-methyl-D-aspartate in cerebral cortex, Brain Res Rev, 02/13/2008

Pituitary adenylate cyclase-activating polypeptide induces pial arteriolar vasodilation through cyclooxygenase-dependent and independent mechanisms in newborn pigs, Brain Res, 01/07/2008

Neuronal preconditioning with the antianginal drug, bepridil, J Neurochem, 11/27/2007

Systemic administration of diazoxide induces delayed preconditioning against transient focal cerebral ischemia in rats, Brain Res, 11/02/2007

Contribution of poly(ADP-ribose) polymerase to postischemic blood-brain barrier damage in rats, J Cereb Blood Flow Metab, 10/12/2007

Abnormal diazoxide induced vasodilation in cerebral arteries from Zucker obese rats with insulin resistance [abstract], FASEB J, 07/23/2007

Acute treatment with rosuvastatin protects obese (Lep ob) mice against transient cerebral ischemia [abstract], FASEB J, 07/23/2007

Abnormal diazoxide-induced vasodilation of middle cerebral arteries following transient focal cerebral ischemia in rats [abstract], FASEB J, 07/23/2007

Neuronal preconditioning with the antianginal drug, Bepridil [abstract], FASEB J, 07/17/2007

Characterization of pituitary adenylyl cyclase activating polypeptide (PACAP)-induced pial arteriolar dilation in piglets [abstract], FASEB J, 07/17/2007

Human heart mitochondria do not produce physiologically relevant quantities of nitric oxide, Life Sci, 05/29/2007

Adaptation of the hypothalamic blood flow to chronic nitric oxide deficiency is independent of vasodilator prostanoids, Brain Res, 04/25/2007

The mitochondrial KATP channel opener BMS-191095 reduces neuronal damage after transient focal cerebral ischemia in rats, J Cereb Blood Flow Metab, 02/14/2007

Myocardial preconditioning against ischemia-reperfusion injury is abolished in Zucker obese rats with insulin resistance, Am J Physiol Regul Integr Comp Physiol, 02/13/2007

Cloning of cyclooxygenase-1b (putative COX-3) in mouse, Inflamm Res, 11/09/2006

Adverse effects of reactive oxygen species on vascular reactivity in insulin resistance, Antioxid Redox Signal, 10/30/2006

Transient glucose and amino acid deprivation induces delayed preconditioning in cultured rat cortical neurons, J Neurochem, 10/19/2006
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

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