Year of Funding | Project Leader | OAIC Pilot/Exploratory Study | Outcomes of Pilot/Exploratory Studies |
2006 | Peter E. Morris, MD
Associate Professor
Pulmonary and Critical Care Medicine | Effect Of Acute Inflammatory Mediators On Duration Of Functional Limitations In Elderly Patients With Acute Respiratory Failure | In Progress |
2006 | Mike Madigan, PhD
Assistant Professor
Engineering Science and Mechanics
VT-WF School of Biomedical Engineering Kevin Davy, PhD
Associate Professor
Human Nutrition, Foods and Exercise
VT-WF School of Biomedical Engineering | Effects of Sarcopenic Obesity on Recovery from a Trip | Completed |
2005 | Delrae Eckman, PhD | PPAR Activators and Physical Function in Old Rats | In Progress |
2005 | Gary Miller, PhD
Health and Exercise Science | Does Weight Loss Following Laparoscopic Roux-en-Y Gastric Bypass Improve Physical Function?” (Pilot) | Completed |
2005 | Erica Hartmann, MD
Internal Medicine and Nephrology | Impact of an Exercise Program on Physical Function, Body Composition, and Quality of Life in Aging Recipients of Renal Allografts (Pilot) | Completed; ASN / ASP Award |
2005 | Jingzhong Ding, MD
Dept. of Internal Medicine Section on Gerontology and Geriatric Medicine | Pericardial fat and subclinical and clinical measures of cardiovascular disease in a multi-ethnic sample of US adults (Pilot) | Completed; R01 funded HL085323 |
2005 | Lynne Wagenknecht, MD
Department of Public Health Sciences, Epidemiology | Metabolic and Genetic Determinants of Non-Alcoholic Fatty Liver Disease in African-American and Hispanic Americans (Pilot) | Completed; 1 paper |
2004 | Craig Hamilton, MD
Biomedical Engineering | Optical Imaging of Skeletal Muscle (Pilot) | Completed |
2004 | Jeff Carr, MD
Radiologic Sciences | Developing CT Measures of Adiposity and Body Composition for Application in Population-based and Genomic Research (Pilot) | Completed; 1 paper |
2004 | Tongjian You, PhD
Dept. of Internal Medicine/Geriatrics | Effects of Caloric Restriction on Physical Performance in Aged Rats (Pilot) | Completed
K award in preparation |
2002-2003 | Gregory Hundley, MD
Dept. of Internal Medicine/Cardiology | Leg blood flow, sarcopenia and physical function (Pilot) | Completed |
2002-2003 | Anthony P. Marsh, PhD
Health and Exercise Science | Power training in older adults: mechanisms underlying change in muscle function (Pilot) | Completed |
2002-2003 | Anthony P. Marsh, PhD
Health and Exercise Science | Effect of muscle power on disability: analyses of the InChianti Study (Exploratory Study) | Completed; Last Draft of Manuscript |
2002-2003 | Capri Foy, PhD
Dept. of Health & Exercise Science | Pro-social Behavior as a Motivation Facilitator of an Exercise Adherence Among Older Adults: A Preliminary Study (Pilot) | Completed; R21 funded. |
2002-2003 | Graziano Onder, MD
Dept. of Internal Medicine/Geriatrics | Effects of ACE inhibitors on skeletal muscle and physical disability in older adults (Exploratory Study) | Completed; Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study.
Lancet. 2002 Mar 16;359(9310):926-30. |
2002-2003 | Dora Il'yasova, PhD
Cancer Control and Prevention | Relationships Between Biomarkers of the Systemic Oxidative Stress 8-ISO-PGF-M, Systemic Inflammatory Markers, and Muscular Function (Pilot) | Completed
K01 in preparation
Manuscript in preparation |
2001-2002 | Suzy Torti, PhD
Biochemistry | IGF1 in Aging and Cancer: Role of Modulation of Iron Metabolism and Oxidative Stress (Pilot) | Completed |
2001-2002 | Osvaldo Delbono, MD, PhD
Dept. of Physiology/Pharmacology
Dep. of Internal Medicine/Geriatrics | Gene therapy of sarcopenia (Pilot) | Completed; Single skeletal muscle impairment with aging. NIH, 5R01AG013934-08 |
2001-2002 | Dalane Kitzman, MD
Dept. of Internal Medicine/Cardiology | Effects of spironolactone on exercise tolerance and quality of life in older subjects with diastolic heart failure (Pilot) | Exercise Intolerance in Elderly Diastolic Heart Failure- R01-recently funded. |
2001-2002 | Dalane Kitzman, MD
Dept. of Internal Medicine/Cardiology | Potential Contribution of Inflammation and Skeletal Muscle Loss to Disability in Older Patients with Diastolic Heart Failure and the Potential Role of ACE-I Therapy (Pilot) | Exercise Intolerance in Elderly Diastolic Heart Failure- R01 has been submitted.
Work continuing to complete trial in 2005. |
2001-2002 | Brenda Penninx, PhD
Dept. of Internal Medicine/Geriatrics | Antidepressants and physical exercise in older persons with minor depression (Pilot) | Completed Manuscript and Grant in Preparation |
2000-2001 | Jeff Williamson, MD
Dept. of Internal Medicine/Geriatrics | Efficacy of exercise with and without ACE inhibition in improving extremity strength, function and muscle mass in older adults (Pilot) | ACE Inhibitors and Functional Decline in High Risk Older Adults, NIH grant application in preparation (2001) |
2000-2001 | Christy S. Carter, PhD
Dept. of Internal Medicine/Geriatrics | Long-term effects of enalapril and rofecoxib on physical performance in aging rats (Pilot) | Modeling preclinical disability in aged rats. NIH, NGA: 3 P60 AG10484-10S1 (PI: Pahor) 2001-2002 |
| | | Modeling preclinical disability in aged rats. NIH, NGA: 1 R03AG019936-01 (PI: Pahor) 2001-2002 |
1999-2000 | Stephen R. Rapp, PhD
Dept. of Psychiatry | Memory improvement trial in seniors (MITIS) (Pilot) | NIH grant application in preparation, 1 paper submitted |
1999-2000 | Reidar Wallin, PhD
Dept. of Internal Medicine | Arterial calcification: a significant problem in aging populations (Pilot) | Vitamin K, Bone, and Arterial Calcification, NIH, RFA# HL-01-014 (PI: Wallin) 9/30/01 - 9/29/05 |
1998-1999 | Mary Lou Voytko, PhD
Dept. of Pathology/Comparative Med. | Cognition and estrogen in aged female monkeys (Pilot) | Cognition and Estrogen in Menopause: A Monkey Model
NIA RO1 AG13204-08 |
1997-1998 | Roger T. Anderson, PhD
Dept. of Public Health Sciences | The Inspire Study: Increasing participation in cardiac rehabilitation (Pilot) | Increasing participation in cardiac rehabilitation by patient activation in primary care settings, revision in progress to send to AHRQ (PI:Anderson) Nov. 2001 |
1997-1998 | Donald Bowden, PhD
Dept. of Biochemistry | Genetic epidemiology of diabetic cardiovascular disease (pilot) | Genetic epidemiology of Diabetic Cardiovascular Disease, American Diabetes Association (PI: Bowden) 01/01/99-12/31/1001 |
Genetic Epidemiology of Subclinical CVD in Type 2 Diabetes, NIH/NHLBI 1 R01 HL67348 (PI: Bowden) 07/15/01-06/30/05 |
1997-1998 | Linda McPhail, PhD
Dept. of Biochemistry | Priming and signaling in neutrophils from elderly individuals (Pilot) | Regulation of oxygen metabolism blood neutrophils, NIH-5R01AI22564-15 (PI:McPhail) 1985-2001 |
1995-1996 | William Moran, MD
Dept. of General Internal Medicine | Community resources advocate (Pilot) | Community Volunteer Program, Kate B. Reynolds Foundation, 1996-1999 (PI:Moran) |
1995-1996 | W. Jack Rejeski, PhD Dep. of Health & Exercise Sciences | Shaping Active Living in the Elderly (Pilot) | Cardiovascular Health and Activity Maintenance (CHAMP) NIH-3P60AG10484-07S10005 (PI: Rejeski) 1997-2001 |
1995-1996 | Stuart Cohen, EdD | Mature Adult Passport (Pilot) | A Health Guide to optimize the health of older adults , National Institute of Aging, (PI:Dugan) 9/98-10/99 |
A Health Guide to optimize the health of Hispanic women, Dept. of Health and Human Services. (PI: Dugan) 5/99-4/00 |
1994-1995 | Cathy Carlson, DVM, PhD | MRI for knee OA in monkeys (Pilot) | Development of a Congestive Heart Failure Guide, funded through the CDC and the American Association of Health Plans. |
New techniques in diagnosing osteoarthritis, NIH-5R01RR14099-09 (PI:Carlson) 1993-2006 |
1994-1995 | William Cefalu, PhD
Dept. of Medicine, University of Vermont College of Medicine | Effects of caloric restriction on intracellular mechanisms regulating glucose transportation in muscle (Pilot) | Caloric Restriction, Aging and Insulin Action, 1RO1 AG15823 (PI: Cefalu) 1999-2002 |
1994-1995 | Osvaldo Delbono, MD, PhD
Dept. of Physiology & Pharmacology | Skeletal muscle maintenance and repair in the elderly (Pilot) | Mechanisms of Single Skeletal Muscle Fiber Impairment with Aging, NIH-5R29AG13934-03 (PI: Delbono) 1997-2002 |
Age-dependent regulation of excitation-contraction coupling RO1 AG15820-03 (PI: Delbono) 1998-2003 |
| | | Skeletal Muscle Impairment in Aging, NIH-5K01AG00692-04 (PI: Delbono) 1996-2001 |
1994-1995 | Iris J. Edwards, PhD
Dept. of Pathology/Comparative Med. | The role of proteoglycans in metabolism of advanced glycosylation end products and arterial cells (Pilot) | Dietary Restriction & Aging in Rhesus Monkeys, NIA-5P51RR00167-390046 (PI:Weindruch), (PI:Edwards,Consortium Agreement) 1976-2002 |
Aging, Arterial Proteoglycans and Caloric Restriction, NIA RO3 AG14190-01A1 (PI:Edwards) 1997-1999 |
Proteoglycan - Lipoprotein Interaction in Diabetes, ADA (PI:Edwards) |
1994-1995 | Richard Loeser, MD | IGF-1 and Matrix Repair in Articular Cartilage (Pilot) | IGF-1 and matrix repair in articular cartilage, Paul Beeson physician faculty scholar research award, American federation for aging research (PI: Loeser) |
Aging and IF1 in Cartilage, NIH 1R01AG016697-01A1 (PI: Loeser) 2001-2005 |
1994-1995 | Sally Shumaker, PhD
Dept. of Public Health Sciences | Enhancing Recovery from Breast Cancer (Pilot) | Exercise and Quality of Life in Women with Breast Cancer, NIH-1R55CA78418-01A1 (PI: Shumaker) 1999-2001 |
Research on optimal recovery practices in breast cancer (RESTORE) - DOD grant (PI Anderson) 2001-2005 |
1993-1994 | Steve Messier, PhD
Dept. of Health & Exercise Sciences | Lifestyle Intervention Study in Seniors with Arthritis (Pilot) | Arthritis, Diet and Activity Promotion Trial (ADAPT), OAIC intervention study 1997-2002, NIH-NIA P60 AG10484 (PI: Messier) |
Gene Polymorphisms and Prevention of Disability, 1 R01 AG18702-01A1 (PI:Pahor) 2001-2004 |
1993-1994 | Michael Berry, PhD
Dept. of Health & Exercise Sciences | Exercise and disability in COPD patients (Pilot) | Exercise to Prevent Disability and Cardiovascular Events, NGA 1 R21 AG19353-01 (PI: Pahor) 2001-2002 |
Exercise and Disability in COPD Patients (REACT) NIH, 1R01 HL053755-O1A1 PI:Berry) 1995-2000 |
Exercise and Disability in COPD Patients (REACT 2) NIH, 2R01 HL053755-O5A1 (PI:Berry) 2001-2006 |
1993-1995 | Dalane Kitzman, MD
Dept. of Internal Medicine/Cardiology | Exercise and congestive heart failure (Pilot) | Exercise Training/Diastolic Heart Failure in the Elderly, NIH-5R01AG12257-03 (PI:Kitzman) (PARIS) 1994-1997 |
Exercise Training/Diastolic Heart Failure in the Elderly, NIH-5R01AG12257-07 (PI:Kitzman) (PARIS II)1998-2002 |
Exercise Intolerance in Elderly Diastolic Heart Failure (PIE), NIH, RO1-AG18915) (PI:Kitzman) 2001-2005 |
1992-1993 | David Sundberg, PhD
(deceased) | Central peptidergic function in the aging female: steroid therapy (Pilot) | Central oxytocin in the aging female: steroid therapy, NIH-R01AG10850-01 (PI Sundberg) |
1992-1993 | James Johnson, PhD
Dept. of Pathology/Comparative Med. | Development of a human retinal research bank for aging studies (Pilot) | 1 abstract |
1992-1993 | Richard Webber, PhD
Dept. of Dentistry | Assay of chronic changes in trabecular bone to determine correlates with osteoporosis (Pilot) | Variable aperture dental tomosynthetic X ray system, NIH-5R01DE12227-03 (PI:Webber) 1997-2001 |
1992-1993 | Stephen R. Rapp, PhD
Dept. of Psychiatry | Caregiver and patient functioning in dementia: The role of caregiver skills (Pilot) | 5 papers |
1992-1993 | W. Jack Rejeski, PhD
Health & Exercise Sciences | Pepper Center Functional Status Index: Development and Validation (Pilot) | 1 paper, instrument used in at least 10 future OAIC studies |