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ZK Shihabi PhD

Zakariya K. Shihabi, PhD Professor of Pathology (Clinical Pathology) Director: Clinical Chemistry Board Certification: American Board of Clinical Chemistry; National Registry in Clinical Chemistry   Education: Undergraduate: University of Alexandria, Egypt, BS 1961 Postgraduate: Texas A&M University, MSc 1965; University of South Dakota, PhD 1970 Fellowship: University of Buffalo School of Medicine, Clinical Chemistry 1970-1972 Interests: Teaching: Clinical Chemistry; Automation; Chromatography; Clinical Enzymology; Immunoassay Methods; Capillary Electrophoresis Research: Application of Automation and Chromatography in Clinical Chemistry; Excretion of Different Proteins in Diabetes and Hypertension Clinical: Taurine Metabolism; Proteinuria in Diabetes; Nonenzymatic Glycosylation of Proteins in Diabetes; Phytoestrogens Dr. Zak Shihabi Tel: (336) 716-2639 Fax: (336) 716-7595 zshihabi@wfubmc.edu Recent Publications: Shihabi ZK. Direct injection of organic solvent extracts for capillary electrophoresis. Electrophoresis. 2008 May;29(8):1672-5. Peacock TP, Shihabi ZK, Bleyer AJ, Dolbare EL, Byers JR, Knovich MA, Calles-Escandon J, Russell GB, Freedman BI. Comparison of glycated albumin and hemoglobin A(1c) levels in diabetic subjects on hemodialysis. Kidney Int. 2008 May;73 Shihabi ZK. Cryoglobulins: an important but neglected clinical test. Ann Clin Lab Sci. 2006 Autumn;36(4):395-408. Shihabi ZK. Direct analysis of hydrogen peroxide by capillary electrophoresis. Electrophoresis. 2006 Nov;27(21):4215-8. Cheng CP, Cheng HJ, Cunningham C, Shihabi ZK, Sane DC, Wannenburg T, Little WC. Angiotensin II type 1 receptor blockade prevents alcoholic cardiomyopathy. Circulation. 2006 Jul 18;114(3):226-36. Shihabi ZK, Hinsdale ME. Serum iohexol analysis by micellar electrokinetic capillary chromatography. Electrophoresis. 2006 Jun;27(12):2458-63. Foreman JE, Blizard DA, Gerhard G, Mack HA, Lang DH, Van Nimwegen KL, Vogler GP, Stout JT, Shihabi ZK, Griffith JW, Lakoski JM, McClearn GE, Vandenbergh DJ. Serum alkaline phosphatase activity is regulated by a chromosomal region containing the alkaline phosphatase 2 gene (Akp2) in C57BL/6J and DBA/2J mice. Physiol Genomics. 2005 Nov 17;23(3):295-303. Shihabi ZK. Organic solvent high-field amplified stacking for basic compounds in capillary electrophoresis. J Chromatogr A. 2005 Feb 25;1066(1-2):205-10. Brucks S, Little WC, Chao T, Kitzman DW, Wesley-Farrington D, Gandhi S, Shihabi ZK. Contribution of left ventricular diastolic dysfunction to heart failure regardless of ejection fraction. Am J Cardiol. 2005 Mar 1;95(5):603-6. Shihabi ZK, Hinsdale ME. Simplified hemoglobin chain detection by capillary electrophoresis. Electrophoresis. 2005 Feb;26(3):581-5. Shihabi ZK. Fenofibrate and fenofibric acid analysis by capillary electrophoresis. Electrophoresis. 2004 Jun;25(10-11):1648-51. Shihabi ZK. Effect of sample composition on electrophoretic migration application to hemoglobin analysis by capillary electrophoresis and agarose electrophoresis. J Chromatogr A. 2004 Feb 20;1027(1-2):179-84. Shihabi ZK, Hinsdale ME, Bleyer AJ. Analysis of Tamm-Horsfall protein by high-performance liquid chromatography with native fluorescence. J Chromatogr A. 2004 Feb 20;1027(1-2):161-6. Shihabi ZK, Oles K, Hinsdale M. Analysis of the antiepileptic drug keppra by capillary electrophoresis. J Chromatogr A. 2003 Jul 4;1004(1-2):9-12. Tharp AM, Woodruff RD, Shihabi ZK. IgD-kappa myeloma: an unusual case. Ann Clin Lab Sci. 2003 Winter;33(1):97-100. Brucks S, Gandhi SK, Mazur W, Kitzman DW, Shihabi ZK, Little WC. What differentiates diastolic from systolic heart failure? [abstract]. J Am Coll Cardiol 2003;41(6 Suppl A):173A. Shihabi ZK. Stacking by electroinjection with discontinuous buffers in capillary zone electrophoresis. Electrophoresis. 2002 Aug;23(15):2394-8. Shihabi ZK. Stacking for nonaqueous capillary electrophoresis. Electrophoresis. 2002 Jun;23(11):1628-32. Shihabi ZK. Transient pseudo-isotachophoresis for sample concentration in capillary electrophoresis. Electrophoresis. 2002 Jun;23(11):1612-7. Erikson KM, Shihabi ZK, Aschner JL, Aschner M. Manganese accumulates in iron-deficient rat brain regions in a heterogeneous fashion and is associated with neurochemical alterations. Biol Trace Elem Res. 2002 Summer;87(1-3):143-56. Kirk JK, Konen JC, Shihabi Z, Rocco MV, Summerson JH. Effects of Terazosin on Glycemic Control, Cholesterol, and Microalbuminuria in Patients with Non--Insulin-Dependent Diabetes Mellitus and Hypertension. Am J Ther. 1996 Sep;3(9):616-621. Pugia MJ, Wallace JF, Lott JA, Sommer R, Luke KE, Shihabi ZK, Sheehan M, Bucksa JM. Albuminuria and proteinuria in hospitalized patients as measured by quantitative and dipstick methods. J Clin Lab Anal. 2001;15(5):295-300. Wallace JF, Pugia MJ, Lott JA, Luke KE, Shihabi ZK, Sheehan M, Bucksa JM. Multisite evaluation of a new dipstick for albumin, protein, and creatinine. J Clin Lab Anal. 2001;15(5):231-5. Shihabi ZK, Hinsdale ME, Cheng CP. Analysis of glutathione by capillary electrophoresis based on sample stacking. Electrophoresis. 2001 Jul;22(11):2351-3. Shihabi ZK, Schwartz RP, Pugia MJ. Decreasing the variability observed in urine analysis. Ann Clin Lab Sci. 2001 Jan;31(1):99-102. Shihabi ZK. Stacking in capillary zone electrophoresis. J Chromatogr A. 2000 Dec 1;902(1):107-17. Review.