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James C. Eisenach, M.D.

James C. Eisenach, M.D.

Professor, Anesthesiology-Obstetric and Gynecologic Anesthesia
Women's Center of Excellence
Contact Information
Office:
336-716-2011
Clinical Specialties
Obstetrical Anesthesia, Pain Research
Education & Training
  BAUniversity of Nebraska-Lincoln1976
  MSCalifornia Institute of Technology1978
  MDUniversity of California Schl of Med-SanFrancisco1982
ResidencyAnesthesiologyMayo Clinic1985
InternshipMedicineMount Zion Hosp & Med Ctr1983
Board Certifications
American Board of Anesthesiology
Memberships
Int'L Association For The Study of Pain
American Society of Clinical Oncology
American Society of Mass Spectrometry
American Medical Association
American Pain Society
Col.Of Chest Physicians
Consortium of Se Hypertension Centers
Int'L Anesthesia Research Society
American Society of Anesthesiologists
Association of University Anesthesiologists
NPI Number
1932184801
James C. Eisenach, M.D.

James C. Eisenach, M.D.

Professor, Anesthesiology-Obstetric and Gynecologic Anesthesia
Women's Center of Excellence
Contact Information
Office:
336-716-2011
Research Interests
human, adult, anesthesiology, translational research, clinical trials, drugs/therapeutic agents pharm, cardiovascular system
Recent Publications
Is CSF oxytocin concentration different between immediate postpartum and non-peripartum patients? [abstract], In: Abstracts of the 2009 Annual Meeting of the American Society of Anesthesiologists (ASA); 2009 Oct 17-21; New Orleans (LA), 11/16/2009

Are signposts in the woods pointing in the right direction? [letter], Anesthesiology, 11/09/2009

Comparison of heat hyperalgesia following intravenous administration of naloxone and remifentanil [abstract], Soc Neurosci Abstr, 10/29/2009

Neostigmine decreases bupivacaine use by patient-controlled epidural analgesia during labor: a randomized controlled study, Anesth Analg, 10/08/2009

Epidural neostigmine: will it replace lipid soluble opioids for postoperative and labor analgesia? [editorial], Anesth Analg, 10/06/2009

Psychophysical differences between mechanical pressure pain and heat pain [abstract], In: Abstracts of the 12th World Congress on Pain [on CD], 08/12/2009

The pain of childbirth and its effect on the mother and the fetus, Chestnut's obstetric anesthesia: principles and practice. 4th ed, 07/21/2009

Curiosity, discipline, and joy; and the greatest of these is joy [editorial], Anesthesiology, 06/18/2009

The effect of peripherally administered CDP-choline in an acute inflammatory pain model: the role of alpha7 nicotinic acetylcholine receptor, Anesth Analg, 05/07/2009

Data fabrication and article retraction: how not to get lost in the woods [editorial], Anesthesiology, 05/04/2009

Fospropofol assay issues and impact on pharmacokinetic and pharmacodynamic evaluation [reply to letter], Anesth Analg, 03/13/2009

Reply to Fospropofol assay: issues and impact on pharmacokinetic and pharmacodynamic evaluation [reply to letter], Eur J Anaesthesiol, 03/06/2009

2008 in review: advancing medicine in anesthesiology, Anesthesiology, 01/09/2009

Gabapentin acts within the locus coeruleus to alleviate neuropathic pain, Anesthesiology, 01/09/2009

A simple model for predicting postcesarean section pain and analgesic requirement [abstract], Anesthesiology, 12/09/2008

Animal models and the prediction of efficacy in clinical trials of analgesic drugs: a critical appraisal and call for uniform reporting standards, Pain, 12/08/2008

Fospropofol assay issues and impact on pharmacokinetic and pharmacodynamic evaluation [reply to letter], Anesthesiology, 12/05/2008

Multiplicative interactions to enhance gabapentin to treat neuropathic pain, Eur J Pharmacol, 12/05/2008

Severity of acute pain after childbirth, but not type of delivery, predicts persistent pain and postpartum depression, Pain, 12/05/2008

Journal-related and other special activities at the 2008 American Society of Anesthesiologists Annual Meeting, Anesthesiology, 11/25/2008

Regional anesthesia: advancing the practice of medicine; the 2008 Gaston Labat Award lecture, Reg Anesth Pain Med, 11/20/2008

Anesthesiology, its mission, and 2007's 'best' articles [reply to letter], Anesthesiology, 10/16/2008

Science and the mission of Anesthesiology [editorial], Anesthesiology, 10/16/2008

Electrophysiologic characteristics of large neurons in dorsal root ganglia during development and after hind paw incision in the rat, Anesthesiology, 10/01/2008

Pain: mechanism and activity at the spinal cord, Refresher Courses Anesthesiol, 08/20/2008

Brain derived nerve growth factor induces spinal noradrenergic fiber sprouting and enhances clonidine analgesia following nerve injury in rats, Pain, 07/08/2008

Pregnancy increases excitability of mechanosensitive afferents innervating the uterine cervix, Anesthesiology, 06/30/2008

Assessment of behavior during labor in rats and effect of intrathecal morphine, Anesthesiology, 06/30/2008

Toxicology profile of N-methyl-D-aspartate antagonists delivered by intrathecal infusion in the canine model, Anesthesiology, 06/24/2008

ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A-or alpha-2C-adrenergic receptors, J Pharmacol Exp Ther, 02/04/2008

2007 in review: a dozen steps forward in anesthesiology, Anesthesiology, 01/30/2008

Incidence of chronic pain after vaginal or cesarean delivery and predictive factors [abstract], Swiss Med Wkly, 01/16/2008

Predictive factors of acute pain after delivery [abstract], Swiss Med Wkly, 01/16/2008

Predictive factors for chronic pain at 8 weeks after vaginal or cesarean deliveries [abstract], Anesthesiology, 12/17/2007

Assessment of labor pain in rats: an experimental behavioral approach [abstract], Anesthesiology, 12/17/2007

Electrophysiological changes of uterine cervical mechanosensitive afferents during pregnancy [abstract], Anesthesiology, 12/17/2007

Chronic pain after delivery--is it different between vaginal and operative deliveries? [abstract], Anesthesiology, 12/17/2007

Clonidine reduces hypersensitivity and alters the balance of pro- and anti-inflammatory leukocytes after local injection at the site of inflammatory neuritis, Brain Behav Immun, 10/12/2007

Anesthesiology and the press [editorial], Anesthesiology, 10/05/2007

Chronic pain after delivery--is it different between vaginal and operative deliveries? [abstract], Anesthesiology, 07/30/2007

Oral gabapentin activates spinal cholinergic circuits to reduce hypersensitivity after peripheral nerve injury and interacts synergistically with oral donepezil, Anesthesiology, 07/18/2007

Predictive factors for chronic pain at 8 weeks after vaginal or cesarean deliveries [abstract], Anesthesiology, 07/12/2007

Predictive factors for acute pain after vaginal and cesarean deliveries [abstract], Anesthesiology, 07/12/2007

Effect of spinal versus epidural analgesia on uterine cervical dilation and cytokine expression in laboring women [abstract], Anesthesiology, 07/12/2007

Estrogen amplifies pain responses to uterine cervical distension in rats by altering transient receptor potential-1 function, Anesth Analg, 06/12/2007

Oral donepezil reduces hypersensitivity after nerve injury by a spinal muscarinic receptor mechanism, Anesthesiology, 06/12/2007

Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision, Anesthesiology, 05/21/2007

Gabapentin activates spinal noradrenergic activity in rats and humans and reduces hypersensitivity after surgery, Anesthesiology, 04/25/2007

Analgesia induced by perineural clonidine is enhanced in persistent neuritis, Neuroreport, 03/28/2007

Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics, Anesthesiology, 03/27/2007

Clonidine maintains intrathecal self-administration in rats following spinal nerve ligation, Pain, 01/30/2007

Can you imagine that? Progress in communication in medicine [editorial], Anesthesiology, 01/22/2007

Neuronal nitric oxide synthase is upregulated in a subset of primary sensory afferents after nerve injury which are necessary for analgesia from alpha2-adrenoceptor stimulation, Brain Res, 01/16/2007

Spinal glial activation contributes to postoperative mechanical hypersensitivity in the rat, J Pain, 01/11/2007

A pain model after gynecologic surgery: the effect of intrathecal and systemic morphine, Anesth Analg, 12/18/2006

Chronic activation of spinal adenosine A1 receptors results in hypersensitivity, Neuroreport, 12/05/2006

Perineural clonidine reduces p38 mitogen-activated protein kinase activation in sensory neurons, Neuroreport, 11/07/2006

Intrathecal administration of a cylcooxygenase-1, but not a cyclooxygenase-2 inhibitor, reverses the effects of laparotomy on exploratory activity in rats, Anesth Analg, 11/07/2006

Developmental differences in microglia activation in the spinal cord after paw incision in the rat [abstract], Anesthesiology, 11/06/2006

CSF concentration does not predict onset or duration of spinal fentanyl for labor analgesia [abstract], Anesthesiology, 11/06/2006

Spinal cord dynorphin expression increases, but does not drive microglial prostaglandin production or mechanical hypersensitivity after incisional surgery in rats, Pain, 10/12/2006
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

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