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Clinical Trial in Multiple Sclerosis

 

Active Enrolling

 

Active Closed for Enrollment

  • Achieve 9013 - compare the total number of confirmed relapses experienced by the patients randomized to continue their current high-dose of IFN therapy (Betaseron® 250 µg or Rebif® 44 µg) to that observed in patients randomized to GA (Copaxone®) treatment
  • Pre-Beyond 307320 – offer extension of treatment to all patients with RRMS who completed full treatment in the double-blind, randomized, parallel group, multicenter study 307000A, and to further assess the safety and tolerability of Betaseron® 500 µg QOD and 250 µg QOD in these patients
  • Bayer- Beyond Follow-up- International, multicenter, Phase IIIb study of subcutaneous everyother- day treatment of patients with relapsing multiple sclerosis with (Phase A) double-blind Betaseron/Betaferon 250 μg or 500 μg or open-label Betaseron/Betaferon 250 μg and (Phase B) open-label Betaseron/Betaferon 500 μg

    BEYOND Follow-up study

  • Choice DAC-1012 – evaluate the efficacy of daclizumab in patients who have active, relapsing forms of MS and are currently on IFN-beta therapy
  • Regard 24735 – compare the time to first relapse of subjects treated with Rebif® 44 mcg three times per week (132 mcg per week) with that of subjects treated with Copaxone® 20 mg daily during 96 weeks of treatment
  • Pilot Study – A Pilot Study of MRI Spectroscopy, Diffusion Tensor Imaging, and Magnetization Transfer Imaging in multiple sclerosis
  • Forte 9016
  • Serono 27133 Rebif-Betaseron

 

Completed

  • Above – A Randomized, Rater-Blinded, Multicenter, Parallel-group Study Comparing the Efficacy and Safety of Betaseron® 250 mcg Subcutaneously Every Other Day with Avonex 30 mcg Intramuscularly Once per Week in Relapsing-remitting Multiple Sclerosis Patients Previously Treated with Avonex®
  • Beyond 306440 – compare INFB-1b a 500 µg (16 MIU) dose to currently approved dose (250 µg; 8 MIU), given subcutaneously (SC) QOD, with regard to safety, tolerability and efficacy in patients with RRMS
  • Teva Achieve 9013 - compare the total number of confirmed relapses experienced by the patients randomized to continue their current high-dose of IFN therapy (Betaseron® 250 µg or Rebif® 44 µg) to that observed in patients randomized to GA (Copaxone®) treatment.

  • PDL Choice DAC-1012 evaluate the efficacy of daclizumab in patients who have active, relapsing forms of MS and are currently on IFN-beta therapy.

  • Serono Regard 24735compare the time to first relapse of subjects treated with Rebif® 44 mcg three times per week (132 mcg per week) with that of subjects treated with Copaxone® 20 mg daily during 96 weeks of treatment

 

 

 

 

 

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Last Modified: 4/1/2008