Charles H. Tegeler, IV, M.D.
Professor
Director, B Mode Ultrasound
Clinical Interests: Cerebrovascular disease (stroke), general neurology, prevention and treatment of stroke and other cerebrovascular disease. diagnostic and therapeutic uses of ultrasound in these disorders.
EDUCATION:
1979 B.A., University of Missouri, Kansas City, Missouri
1979 M.D., University of Missouri, Kansas City, Missouri
POST DOCTORAL TRAINING:
1982 Internal Medicine Residency, University of Missouri, Kansas City, Missouri
1985 Neurology Residency, University of Texas Health Sciences Center, San Antonio, Texas
SPECIALTY CERTIFICATION:
Internal Medicine
Neurology
LICENSURE:
1989 North Carolina
Raised in Springfield, Missouri, Dr. Tegeler completed undergraduate and medical school training at the University of Missouri-Kansas City (1979). He completed Internal Medicine residency at the University of Missouri-Kansas City Affiliated Hospitals (1982), followed by a Neurology residency at the University of Texas Health Science Center-San Antonio (1985). He joined the Neurology Faculty at UTHSC-SA, where for four and a half years he was active in stroke prevention and treatment trials, and the use of ultrasound in neurologic disorders. Dr. Tegeler moved to Winston-Salem, North Carolina, and joined the Department of Neurology at Bowman Gray School of Medicine of Wake Forest University in 1990. He is now a Professor of Neurology, Director of the Neurosonology Laboratory, and Head of the Section on Stroke and Cerebrovascular Disease. He also was the senior editor for the textbook, Neurosonology (Mosby 1995). Dr. Tegeler is President of the American Society of Neuroimaging (ASN), Chairman of the ASN Neurosonology Examination Committee, Director of the Neurosonology Program at the ASN Annual Meeting, past Associate Editor, and current member of the Editorial Board, of the Journal of Neuroimaging. He is Alternate Delegate to the AMA House of Delegates for the ASN, and represents the NC Neurological Society as a member of the NC Medicare Carrier Advisory Committee. He is President Elect of the Neuroimaging Section of the American Academy of Neurology, and represented the AAN on the Board of Directors, and Chairman of the Transcranial Doppler Committee, of the Intersocietal Commission for Accreditation of Vascular Laboratories (ICAVL) from 1990-1999. Dr. Tegeler is Treasurer of the Neurosonology Research Group of the World Federation of Neurology, and has been Secretary for the International Cerebral Hemodynamics Society. He is Director of the Basic and Advanced Courses in Neurosonology offered at Wake Forest University School of Medicine, in conjunction with the Center for Medical Ultrasound. He is in charge of the weekly Integrated Neurosonology Teaching Conference, serves as tutor for the Year I medical student small group teaching, and Directs Fellowships in Stroke and Cerebrovascular Disease, and Neurosonology. He is also Co-Chair of the Stroke Continuum Committee of the Neurosciences Service Line at WFUBMC.
Dr. Tegeler's research activities focus on various new uses of ultrasound in stroke and cerebrovascular disorders, and the prevention and acute treatment of stroke. He participated in multiple stroke prevention trials including CATS, TASS, SPAF-I, and NASCET, and acute stroke treatment trials using Ancrod, Nimodipine, Citicoline, Lubeluzole, Pro-urokinase, and Clomethiazole. He was Principle Investigator for Prevalence and Natural History of Emboli in Stroke (RO1-NS30720), PI for the ultrasound reading center for SECORDS (NINDS), Co-I for the Ultrasound Reading Center for ARIC (NHLBIHC92-17), and is on the TCD Committee for SONIA (NINDS). He was PI for industry sponsored research projects, including Carotid Volume Flow in Normal Subjects (Philips Ultrasound International), Effect of Imitrex on NTG-induced Headache using TCD (S2B-150: Glaxo), Carotid Thrombus Imaging with DMP-444 (DuPont Merck), and was Co-I for Emboli in Severe Left Ventricular Dysfunction (THISL: DuPont), and Paraspinal Ultrasound in Normal Subjects (SonoMed). He is PI for TCD in Epilepsy (NCBH Developmental Technology Grant), and has also been involved in numerous other minor or unfunded projects.
On the clinical side, Dr. Tegeler serves in the rotation of Attending on the Acute Stroke Neurology inpatient team, and the Neurology Consultation Service, rotates call duties on the Acute Stroke Study Team, and participates in outpatient care in the WFUP Neurology Stroke and Cerebrovascular Disease Clinic. He reads studies in the Neurosonology Laboratory two to three days per week.
Married to Renee Tegeler, MD. (Internal Medicine and Oncology), he has two children, Christopher (13) and Catherine (10). He served as an Elder at St. John's Lutheran Church from 1994-97, and now is a member of Calvary Baptist Church. He enjoys gardening, fishing, and all kinds of sports and outdoor activities with the family
BIBLIOGRAPHY
Book Chapters:
Crouse JR, Tegeler CH. Diagnosis of Vascular Disease. In Crawford MH, DiMarco JP. Cardiology, Mosby International Limited, London, United Kingdom, Publishers, 2000, 9.1-9.9.
Tegeler CH, Ratanakorn D. Carotid Vertebral Duplex Scanning in Secondary Stroke Prevention and Stenting. In Alexandrov A, Editor, Cerebrovascular Ultrasound in Stroke Prevention and Treatment, Blackwell Futura, Elmsford, NY, Publisher, 2004, 161-169.
Tegeler CH, Ratanakorn D. Diagnosis of Vascular Disease. In Crawford MH, DiMarco JP, Paulus WJ, Cardiology, Second Edition, Mosby International Limited, London, United Kingdom, Publishers, 2004, 99-108.
Tegeler CH, Furberg CD. Lessons from Warfarin Trials in Atrial Fibrillation: Missing the Window of Opportunity. In DeMets DL, Furberg CD, Friedman LM, Editors, Data Monitoring in Clinical Trials, Springer Science+Business Media, Inc., Publisher, 2006, 312-319.
Journal Articles:
Hunt KJ, Evans GW, Folsom AR, Sharrett AR, Chambless LE, Tegeler CH, Heiss G. Acoustic shadowing on B-mode ultrasound of the carotid artery predicts ischemic stroke: The Atherosclerosis Risk in Communities (ARIC) Study. Stroke 2001;32:11220-1126.
Reynolds PS, Greenberg JP, Lien LM, Meads DC, Myers LG, Tegeler CH. Ophthalmic artery flow direction on color flow duplex imaging is highly specific for severe carotid stenosis. J Neuroimaging 2002;12:5-8.
Tan TY, Lien LM, Schminke U, Tesh P, Reynolds PS, Tegeler CH. Hemodynamic effects of innominate artery occlusive disease on anterior cerebral artery. J Neuroimaging 2002;12:59-62.
Hwang CS, Shau WY, Tegeler CH. Doppler velocity criteria based on receiver operating characteristic analysis for the detection of threshold carotid stenoses. J Neuroimaging 2002;12:124-130.
Tan TY, Schminke U, Lien LI, Tegeler CH. Subclavian steal syndrome: Can the blood pressure difference between arms predict the severity of steal? J Neuroimaging 2002;12:131-135.
Tan TY, Schminke U, Lien LI, Eicke BM, Tegeler CH. Extracranial internal carotid artery occlusion: The role of common carotid artery volume flow. J Neuroimaging 2002;12:144-147.
Acharya VJ, Acharya JN, Tegeler CH, Morris P, Meads D, O'Donovan CA. Transcranial Doppler ultrasound: a new method of monitoring hemispheric anesthetization during the intracarotid amobarbital procedure. J Neuroimaging 2002;12:153-157.
Ratanakorn D, Myers LG, Tegeler CH. Detection of air microbubbles in the internal jugular vein after intravenous injection of contrast agent for the diagnosis of patent foramen ovale. J Clin Ultrasound 2002;30:506-509.
Hwang CS, Liao KM, Lee JH, Tegeler CH. Measurement of carotid stenosis: Comparisons between duplex and different angiographic grading methods. J Neuroimaging 2003;13:133-139.
Bavis J, Reynolds P, Tegeler C, Clark P. Asymmetric neuroimaging in Creutzfeldt-Jakob disease: a ruse. J Neuroimaging 2003;13:376-379.
Crutchfield KE, Razumovsky AY, Tegeler CH, Mozayeni BR. Differentiating vascular pathophysiological states by objective analysis of flow dynamics. J Neuroimaging 2004;14:97-107.
Sloan MA, Alexandrov AV, Tegeler CH, Spencer MP, et al. Assessment: Transcranial Dopppler ultrasonography. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2004;62:1468-1481.
Togay-Isikay C, Kim J, Betterman K, Andrews C, Meads D, Tesh P, Tegeler C, Oztuna D. Carotid artier tortuosity, kinking, coiling: stroke risk factor, marker, or curiosity? Acta Neurol Bleg 2005;105:68-72.
Tegeler CH, Kim J. Does Doppler detection of asymptomatic embolization predict stroke risk in symptomatic carotid artery stenosis? Nat Clin Pract Neurol 2005;1:12-13.
Likittanasombut P, Reynolds P, Meads D, Tegeler C. . Volume flow rate of common carotid artery measured by Doppler method and color velocity imaging quantification (CVI-Q). J Neuroimaging 2006;16:34-38.
Tegeler CH, Ratanakorn D, Kim J. Advances in carotid ultrasound. Semin Cerebrovasc Dis Stroke 2005;5:74-82.
Ausavarunginrun P, Sabio H, Kim J, Tegeler CH. Dynamic vascular analysis shows a hyperemic flow pattern in sickle cell disease. J Neuroimaging 2006;16:311-17.
Schminke U, Motsch L, Lien LM, Tan TY, Bond MG, Toole JF, Tegeler CH. Screening for high-grade carotid stenosis using a portable ultrasonography instrument. J Neuroimaging 2006; 16:252-259.
Qureshi AI, Alexandrov AV, Tegeler CH, Hobson RW, Baker JD, Hopkins LN.. Guidelines for screening of extracranial carotid artery disease: a statement for healthcare professionals from the multidisciplinary practice guidelines committee of the American Society of Neuroimaging. J Neuroimag 2007;17:19-47.
Alexandrov AV, Sloan MA, Wong LKS, Douville C, Razumovsky AY, Koroshez WJ, Kaps M, Tegeler CH. Practice standards for transcranial Doppler ultrasound: Part I - Test performance. J Neuroimag 2007;17:11-18.