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Mass Spectrometer Facility, a component of the Biomolecular Resource Core Laboratory

Triple Quadrupole Mass Spectrometer

 

Mass Spectrometer Facility
Department of Biochemistry
Wake Forest University School of Medicine
391 Technology Way
Building A1, Room 340
Winston-Salem, NC 27101



The Quattro II gives investigators access to a powerful technology for the analysis of complex lipids, intact proteins, and peptide mixtures. This instrument has the advantage of precise mass measurement at the lower mass range of many lipids coupled with the capability for precursor and neutral loss analysis to identify phospholipid subclasses. Product ion analysis is used to identify the fatty acids carried by the phospholipid. The Quattro II was purchased with grant funds from the NSF Academic Research Infrastructure Program and matching Institutional funds. It was updated with funds from the North Carolina Biotechnology Center and the Winston-Salem Foundation.

Features:

·     Micromass Quattro II

·     Z-spray and nanospray sources

·     Mass accuracy about 0.01%

·     Lower detection limit approximately 2 pmole

·     True precursor and neutral loss analysis

·     Interfaced to an Agilent model 1100 LC with autosampler

·     Capillary column compatible