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The Heart Center at Wake Forest University Baptist Medical Center is a national leader in the treatment of diastolic heart failure, conducting five studies to learn more about effective treatments. 

A recently recognized form of congestive heart failure – in which the heart contracts normally but doesn’t fill with enough blood – results in more deaths nationwide than the more widely known form of the disorder, report researchers in the current issue of Annals of Internal Medicine.

“Even though the recently recognized form, called diastolic heart failure, is less deadly in individuals, it produces more deaths nationwide because of its much higher prevalence,” said Dalane W. Kitzman, M.D., a cardiologist from Wake Forest University Baptist Medical Center. “In our study of older adults with heart failure, over twice as many participants had diastolic heart failure, suggesting that a key to reducing heart failure deaths is successful treatment of this second type.”

For years a controversy within the cardiology community, physicians around the world now recognize the importance of research into this little-known but common type of heart failure.

With the most widely known type of congestive heart failure – systolic heart failure – the heart doesn’t contract strongly enough. With the newly recognized type – diastolic heart failure – the heart’s main chamber doesn’t fill with enough blood. The end result in both types is that the body doesn’t get enough oxygenated blood to meet its demands.

Kitzman said the research is important because many doctors had believed that diastolic heart failure is not as serious as systolic failure.

“People have thought these patients don’t have high mortality,” said Kitzman. “But this research shows that there is significant mortality among elderly people with congestive heart failure – regardless of which type they have. This is a significant public health problem that we need to learn more about treating.”

Congestive heart failure is the most frequent cause of hospitalization in people age 65 and older and accounts for more than 875,000 hospital admissions each year in the United States.

The standard treatments for systolic heart failure, the more widely known form of heart failure, include water pills and medications to expand the blood vessels or increase the force of the heart’s contractions. Most treatments were studied in male populations younger than 65 with systolic failure. However, about 88 percent of heart failure cases occur in the elderly and the majority has diastolic heart failure. Furthermore, the majority of diastolic heart failure patients are women.

 

Heart failure

Definition:

Heart failure, also called congestive heart failure, is a life-threatening condition in which the heart can no longer pump enough blood to the rest of the body.



Alternative Names:

CHF; Congestive heart failure

Causes, incidence, and risk factors:

Heart failure is almost always a chronic, long-term condition, although it can sometimes develop suddenly. This condition may affect the right side, the left side, or both sides of the heart.

As the heart's pumping action is lost, blood may back up into other areas of the body, including:

With heart failure, many organs don't receive enough oxygen and nutrients, which damages them and reduces their ability to function properly. Most areas of the body can be affected when both sides of the heart fail.

The most common causes of heart failure are hypertension (high blood pressure) and coronary artery disease (for example, you have had a heart attack). Other structural or functional causes of heart failure include the following:

Heart failure becomes more common with advancing age. You are also at increased risk for developing heart failure if you are overweight, have diabetes, smoke cigarettes, abuse alcohol, or use cocaine.



Symptoms:

Infants may sweat during feeding (or other exertion).

Some patients with heart failure have no symptoms. In these people, the symptoms may develop only with these conditions:



Signs and tests:

A physical examination may reveal either an irregular or a rapid heartbeat. There may be distended neck veins, enlarged liver, swelling of the limbs (peripheral edema), and signs of fluid around the lungs (pleural effusion).

Listening to the chest with a stethoscope may reveal lung crackles or abnormal heart sounds. Blood pressure may be normal, high, or low.

An enlargement of the heart or decreased heart functioning may be seen on several tests, including the following:

This disease may also alter the following test results:

If excessive fluid has accumulated around the sac surrounding the heart (pericardium), you may need to have the fluid removed through a pericardiocentesis.



Treatment:

If you have heart failure, your doctor will monitor you closely. This means having follow up appointments at least every 3 to 6 months, figuring out any underlying cause and treating it, and periodic testing of your heart function. For example, an ultrasound of your heart, called an echocardiogram, will be done once in awhile to give an estimate of how well your heart is pumping blood with each stroke or beat.

It is also your responsibility to carefully monitor yourself and help manage your condition. One important way to do this is to track your weight on a daily basis. Weight gain can be a sign that you are retaining fluid and that the pump function of your heart is worsening. Make sure you weigh yourself at the same time each day and on the same scale, with little to no clothes on.

Other important measures include:

  • Take your medications as directed. Carry a list of medications with you wherever you go.
  • Limit salt and sodium intake.
  • Don’t smoke.
  • Stay active. For example, walk or ride a stationary bicycle. Your doctor can provide a safe and effective exercise plan based on your degree of heart failure and how well you do on tests that check the strength and function of your heart. DO NOT exercise on days that your weight has gone up from fluid retention or you are not feeling well.
  • Lose weight if you are overweight.
  • Get enough rest, including after exercise, eating, or other activities. This allows your heart to rest as well. Keep your feet elevated to decrease swelling.

Here are some tips to lower your salt and sodium intake:

  • Look for foods that are labeled “low-sodium,” “sodium-free,” “no salt added,” or “unsalted.” Check the total sodium content on food labels. Be especially careful of canned, packaged, and frozen foods. A nutritionist can teach you how to understand these labels.
  • Don’t cook with salt or add salt to what you are eating. Try pepper, garlic, lemon, or other spices for flavor instead. Be careful of packaged spice blends as these often contain salt or salt products (like monosodium glutamate, MSG).
  • Avoid foods that are naturally high in sodium, like anchovies, meats (particularly cured meats, bacon, hot dogs, sausage, bologna, ham, and salami), nuts, olives, pickles, sauerkraut, soy and Worcestershire sauces, tomato and other vegetable juices, and cheese.
  • Take care when eating out. Stick to steamed, grilled, baked, boiled, and broiled foods with no added salt, sauce, or cheese.
  • Use oil and vinegar, rather than bottled dressings, on salads.
  • Eat fresh fruit or sorbet when having dessert.

Your doctor may consider prescribing the following medications:

  • ACE inhibitors such as captopril and enalapril -- these medications open up blood vessels and decrease the work load of the heart. These have become an important part of treatment
  • Diuretics -- there are several types including thiazide, loop diuretics, and potassium-sparing diuretics; they help rid your body of fluid and sodium.
  • Digitalis glycosides -- increase the ability of the heart muscle to contract properly; prevent heart rhythm disturbances
  • Angiotensin receptor blockers (ARBs) such as losartan and candesartan which, like ACE inhibitors, reduce the workload of the heart; this class of drug is especially important for those who cannot tolerate ACE inhibitors
  • Beta-blockers -- this is particularly useful for those with a history of coronary artery disease

Sometimes, hospitalization is required for acute CHF. Hospitalized patients may receive oxygen and intravenous medications such as vasodilators and diuretics. Medicines such as nesiritide (Natrecor) help dilate blood vessels and may also be helpful.

Medicines called inotropic agents help improve the heart's ability to pump blood. Such drugs include dobutamine and milrinone. They are given by IV.

Unstable patients receiving several medications usually need also hemodynamic monitoring with Swan-Ganz catheterization.

Severe cases of CHF require more drastic measures. For example, excess fluid can be removed through dialysis, and circulatory assistance can be provided by implanted devices such as the intra-aortic balloon pump (IABP) and the left ventricular assist device (LVAD). These devices can be life-saving, but they are not permanent solutions. Patients who become dependent on circulatory support will need a heart transplant.

A number of studies have shown that heart failure symptoms can be improved with a special type of pacemaker. It paces both the right and left sides of heart. This is referred to as biventricular pacing or cardiac resynchronization therapy. Ask your provider if you are a candidate for this.



Expectations (prognosis):

Heart failure is a serious disorder that carries a reduced life expectancy. Many forms of heart failure can be controlled with medication, lifestyle change, and correction of any underlying disorder. Heart failure is usually a chronic illness, and it may worsen with infection or other physical stressors.



Complications:

Possible side effects of medications include:



Calling your health care provider:

Call your health care provider if weakness, increased cough or sputum production, sudden weight gain or swelling, or other new or unexplained symptoms develop.

Go to the emergency room or call the local emergency number (such as 911) if you experience severe crushing chest pain, fainting, or rapid and irregular heartbeat (particularly if other symptoms accompany a rapid and irregular heartbeat).



Prevention:

Follow your health care provider's recommendations for treatment of conditions that may cause congestive heart failure. These recommendations may include:

  • Treat your high blood pressure with diet, exercise, and medication if necessary.
  • Treat your high cholesterol with diet, exercise, and medication if necessary.
  • DO NOT smoke
  • Avoid alcohol use
  • Take an ACE inhibitor if you have heart disease, diabetes, or high blood pressure.
  • Treat arrhythmias (abnormal heart rhythms) and keep your heart rate under control.
  • Treat an underlying thyroid disorder.

Also, consider the following lifestyle habits, especially if you have a strong family history of CHF:

  • Reduce salt intake.
  • Exercise


References:

Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, Ganiats TG, et al. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult. J Am Coll Cardiol. 2005;46:1-82.




Review Date:7/17/2006
Reviewed By:Glenn Gandelman, MD, MPH, Assistant Clinical Professor of Medicine, New York Medical College, Valhalla, NY. Review provided by VeriMed Healthcare Network.

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The information on this Website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified healthcare provider. If you have a medical problem or a health-related question, consult your physician or call Health On-Call at 336-716-2255 or 1-800-446-2255.

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Last Modified: 10/19/2006