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clinical trials for the department of dermatology clinical studies center
what is a clinical trial?
Clinical trials are research studies in which people help medical professionals find ways to improve health. Each study tries to answer specific scientific questions and is designed to find safe and effective ways to better prevent, diagnose, and/or treat disease. Before they can begin, all clinical trials must go through a rigorous review process conducted by the Wake Forest University Health Sciences Institutional Review Board to insure that the safety, rights and welfare of human subjects are protected.
why would I want to consider participating in a clinical trial?
As a volunteer in a clinical trial, you have the opportunity to be involved in important research that may bring about advances in science and health care. Volunteers are needed in all areas of research, from trials in healthy volunteers to studies of specific diseases.
who sponsors clinical trials at WFUBMC?
Clinical trials in the Department of Dermatology at Wake Forest University Baptist Medical Center are sponsored by pharmaceutical companies, the National Institutes of Health, and many other organizations.
how do I participate?
If you are interested in enrolling in one of the many clinical trials taking place in Dermatology at Wake Forest University Baptist Medical Center, click on a link below for the study you are interested in.
if you are interested in participating in any of the studies below please call our center at (336)716-3775 for more information.
current trial listings
persistent itching with atopic dermatitis (eczema) [8326]
The purpose of this research study is to determine whether the test cream (SRD174) helps to relieve pruritus (itching) in people with atopic dermatitis. Also to assess how well a subject responds to the study drug following the treatment of pruritus with SRD174 cream and how safe it is compared to a placebo (a cream that looks like SRD174 but does not contain active ingredient).
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atopic dermatitis (eczema) heart rate patterns [2115]
The purpose of this research is to study heart rate patterns in people with moderate to servere atopic dermatitis and how itching affects thsoe patterns.
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sleep disturbance in atopic dermatitis [46]
The purpose of this research is to study the sleep patterns of people with atopic dermatitis, and how itching affects those patterns.
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atopic dermatitis (eczema) in children [2300]
The purpose of this research study is to better understand how the study drug works when people use them to treat atopic dermatitis. Protopic® has been approved by the US Food and Drug Administration (FDA) for atopic dermatitis (Eczema). Everyone will receive active study medication, Protopic®.
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atopic dermatitis (eczema) [6468]
The purpose of this research study is to better understand how fluocinonide cream 0.1% (Vanos®) works when people use it to treat atopic dermatitis for just a few days. This type of study has not been done before.
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cutaneous t-cell lymphoma [3344]
The purpose of this study is to study how well and how fast a research drug may be effective in treating Cutaneous T-Cell Lymphoma and how safe it is and how well people tolerate the drug.
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hand eczema (severe) [7888]
The purpose of this study is to assess the effectiveness and safety of Alitretinoin® and to compare it to placebo (does not contain active medication) in people with severe chronic hand eczema. Placebo is a capsule that looks like Alitretinoin® but has no active ingredient. Alitretinoin® is an investigational drug. An “investigational drug” is a drug that is being tested and is not approved for sale in the United States by the U.S. Food and Drug Administration (FDA).
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hives or dermatographism [6469]
The purpose of this study is to look at the effects of levocetirizine (Xyzal) on skin levels of histamine (a chemical in the skin) in patients with dermatographism (a condition where lightly scratching the skin raises wheals or welts) & chronic idiopathic urticaria (hives).
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the perception of itch in atopic dermatitis and healthy individuals [2112]
The purpose of this research study is to assess whether seeing other people itch affects itch perception in patients with atopic dermatitis and healthy subjects.
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psoriasis on the elbows and/or knees [7437]
Researchers want to find out if using Olux-E™(Clobetasol Propionate 0.05%) foam or Clobex® (Clobetasol Propionate 0.05%) lotion works better for control of psoriasis.
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