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Core Faculty

Steven A. Akman, MD  My laboratory is interested in DNA damage and mutagenesis.  Faculty Page  Laboratory Page 

Isabelle Berquin, PhD  My laboratory is currently investigating the mechanism by which YB-1 promotes breast cancer, and the effect of dietary lipids on breast and prostate cancer risk.  Faculty Page  Laboratory Page

Yong Q. Chen, PhD My research focuses on two areas of prostate cancer; (1) genetic basis and lipid signaling in prostate cancer development, and (2) effect of dietary fat on prostate cancer development in genetically predisposed populations.  Faculty Page  Laboratory Page

Scott D. Cramer, PhD The current focus of my research is on the molecular dissection of signaling pathways in prostatic cells, the identification of prostate progenitor or stem cells, and understanding epithelial-stromal interactions in normal and abnormal ductal morphogenesis.  Faculty Page    Laboratory Page

William H. Gmeiner, PhD  Research in my laboratory is focused on developing novel cytotoxic oligodeoxynucleotides (ODNs) for treatment of prostate cancer and other malignancies and in understanding the role of DNA structure in carcinogenesis and cancer chemotherapy.  Faculty Page  Laboratory Page

Steven Kridel, PhD  Research in my lab focuses on understanding the regulation of pathways that control fatty acid synthesis by fatty acid synthase in prostate cancer.  Faculty Page  Laboratory Page

George Kulik, PhD  My laboratory is focusing on signal transduction mechanisms that protect prostate cancer cells from apoptosis. This information is necessary to design more effective therapies for advanced prostate cancer and other therapy resistant cancers.  Faculty Page  Laboratory Page

Lance D. Miller, PhD  Using genomic technologies such as DNA microarrays, my laboratory investigates the transcriptional dynamics and genomic architectures of primary tumors to uncover novel prognostic biomarkers and mechanisms of disease progression.  Faculty Page  Laboratory Page

Mark Miller, PhD  Research in my laboratory is examining environmental/genetic interactions that affect an organism’s susceptibility to lung cancer formation, utilizing a variety of in vivo models and molecular biological techniques.  Faculty Page  Laboratory Page

Karin D. Scarpinato, PhD  One of the main DNA repair pathways, mismatch repair (MMR) significantly contributes to the maintenance of genome stability and the elimination of extensively damaged cells.  Faculty Page  Laboratory Page

Darren F. Seals, PhD  Our  lab  is  interested  in  the  basic  mechanisms  of  cell  migration  and  invasion,  particularly  as  it  relates  to  tumor  growth  and  metastasis.  Faculty Page  Laboratory Page

Guangchao Sui, PhD  The research in our lab focuses on the molecular mechanisms of the epigenetic regulation of tumorigenesis.  Faculty Page  Laboratory Page

Gary G.Schwartz, PhD, MPH, PhD  We have suggested that the descriptive epidemiology of prostate cancer, i.e., the increasing risk with age, Black race, and residence at northern latitudes, resemble the descriptive epidemiology of vitamin D deficiency in the elderly.  Faculty Page  Laboratory Page

Frank Torti, MD  The Frank Torti Laboratory is interested in cytokines, such as tumor necrosis factor alpha (TNF), as well as oxidative stress and DNA Damaging agents, such as radiation and chemotherapeutic agents and how they differentially affect the iron homeostatic mechanisms of normal cells and cancer cells.  Faculty Page  Laboratory Page

Jim Vaughn, PhD  The Vaughn laboratory is focused on assaying the anti-tumor therapeutic potential of new classes of chemically modified DNA oligonucleotides.  Faculty Page  Laboratory Page

News & Highlights

The Comprehensive Cancer Center at Wake Forest University Baptist Medical Center has been awarded a grant from the...

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Researchers at Wake Forest University School of Medicine and the University of Wisconsin-Madison have discovered that...

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Quick Reference

Cancer Biology
Telephone 
336-716-9132
Fax 
336-716-0255
E-mail 
Graduate Program E-mail 
Location
Wake Forest University School of Medicine
Medical Center Boulevard
Winston-Salem, NC  27157

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