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Steven J. Kridel, Ph.D.

Associate Professor, Cancer Biology

Contact Information

Office:

336-716-2011

Education & Training

	Degree	Organization	Issued
	BSc	Cal State University-Los Angeles	1992
	PhD	University of California-Irvine	1997

Steven J. Kridel, Ph.D.

Associate Professor, Cancer Biology

Contact Information

Office:

336-716-2011

Research Interests

radiology/imaging, metabolism, cancer/oncogenesis, human, cells only, basic mechanisms, animals, whole, biological/chemical compounds

Recent Publications

Fatty acid synthase activity in tumor cells, Subcell Biochem, 03/10/2009

Disruption of crosstalk between the fatty acid synthesis and proteasome pathways enhances unfolded protein response signaling and cell death, Mol Cancer Ther, 03/10/2009

Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways, Cancer Res, 02/10/2009

1-C-11-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer, J Nucl Med, 04/09/2008

Dietary fat-gene interactions in cancer, Cancer Metastasis Rev, 01/30/2008

Fatty acid synthase inhibitors: new directions for oncology, Expert Opin Investig Drugs, 01/07/2008

Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library, Cancer Res, 12/03/2007

Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat, Nat Struct Mol Biol, 10/09/2007

Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells, Cancer Res, 04/26/2007

Fatty acid synthase: a novel target for antiglioma therapy, Br J Cancer, 11/14/2006

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

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