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Racquel Collins-Underwood Year Matriculated: 2003
Lab: Mike Robbins
Research Interest: My research in Dr. Robbin’s laboratory focuses on the role of chronic oxidative stress in the development and progression of radiation-induced brain injury.
E-Mail: rcollins@wfubmc.edu
Telephone: 336-716-7629 | Joy Little Year Matriculated: 2003
Lab: Steve Kridel
Research Interest: My project in the Kridel lab focuses on delineating the mechanism of cell death induced by Fatty Acid Synthase (FAS) inhibitors in prostate tumor cells. A better understanding of how FAS inhibitors work in tumor cells is crucial to developing these drugs as anti-tumor agents and understanding the biology of FAS-overexpressing tumors.
E-Mail: jlittle@wfubmc.edu
Telephone: 336-716-6752 |
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Alix Norris Year Matriculated: 2003
Lab: Karin Scarpinato
Research Interest: My research in Dr. Scarpinato’s laboratory is focused on mismatch repair (MMR) defects in DNA and their association with carcinogenesis of both hereditary and sporadic types of cancer.
E-Mail: anorris@wfubmc.edu
Telephone: 336-716-8353 | Ryan Topping Year Matriculated: 2003
Lab: Karin Scarpinato
Research Interest: The focus of my research in Dr. Scarpinato’s laboratory is the study of human DNA mismatch repair (MMR) proteins, in particular, the involvement of MMR proteins in programmed cell death, or apoptosis.
E-Mail: rtopping@wfubmc.edu
Telephone: 336-716-8353 |
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Diane Fels Year Matriculated: 2002
Lab:
Research Interest: My project in Dr. Koumenis’s laboratory focuses on using hairpin inhibitory RNAs (ShRNA), to reduce PERK expression in tumor cells, thereby making the cells more sensitive to hypoxic stress, which in turn promote cell death.
E-Mail: dfels@wfubmc.edu
Telephone: 336-713-7632 | Adrienne Smith Year Matriculated: 2002
Lab: George Kulik
Research Interest: My research in Dr. Kulik’s laboratory involves the signaling mechanisms that enable advanced metastatic prostate cancer to resist traditional chemotherapy treatments. I have focused on the PI3K/AKT pathway which leads to the phosphorylation of BAD.
E-Mail: adsmith@wfubmc.edu
Telephone: 336-713-7644 |
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Pameeka Smith Year Matriculated: 2002
Lab: Mike Robbins
Research Interest: The focus of my research in Dr. Robbin’s laboratory is to elucidate the role of reactive oxygen species (ROS) in gliomas. Our goal is to investigate the mechanisms of ROS signaling for survival and death in gliomas which may provide clues to concerning glioma resistance to treatment.
E-Mail: pamesmit@wfubmc.edu
Telephone: 336-716-7629 | Michael A. Thomas Year Matriculated: 2002
Lab: David Ornelles
Research Interest: The work that I have embarked on in Dr. Ornelles’ laboratory has at its core understanding the mechanism that accounts for the G1 restriction imposed on the E1B-55K-mutant virus. A greater understanding of this phenomenon may reveal how this virus can be manipulated to improve its therapeutic index in the treatment of human cancer.
E-Mail: michaelat@wfubmc.edu
Telephone: 336-716-9331 |
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Steve Creacy Year Matriculated: 2001 Lab: Jim Vaughn
Research Interest: In the lab of Dr. Vaughn and in collaboration with Dr. Akman, I am studying a novel helicase enzyme called G4 Resolvase (G4R1). This enzyme specifically recognizes G4 structures in DNA and RNA and melts them. It is possible that G4 Resolvase will serve as an attractive cancer drug target.
E-Mail: screacy@wfubmc.edu
Telephone: 336-716-7123 | |