School of Medicine

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Linda C. McPhail, Ph.D.

Professor, Biochemistry

Women's Center of Excellence

Contact Information

Office:

336-716-2621

Education & Training

	Degree	Organization	Issued
	BS	Methodist College	1970
	MS	Wake Forest University	1973
	PhD	Wake Forest University	1976
Fellowship		Natl Jewish Hosp/Res Ctr	1980

Memberships

American Society of Biological Chemists

American Association of Advancement of Science

American Society of Cell Biology

Linda C. McPhail, Ph.D.

Professor, Biochemistry

Women's Center of Excellence

Contact Information

Office:

336-716-2621

Research Interests

basic mechanisms, immunology/allergy/inflammatio, vascular diseases, human, cells only, molecular biology/molecular me, hematologic system, hormones/cytokines/signalling

Recent Publications

Effect of splice-site mutations in X-linked chronic granulomatous disease [reply to letter], Clin Immunol, 05/04/2009

Mutations in the PX-SH3A linker of p47phox decouple PI(3,4)P2 binding from NADPH oxidase activation, Biochemistry, 12/03/2008

X-linked chronic granulomatous disease secondary to skewed X chromosome inactivation in a female with a novel CYBB mutation and late presentation, Clin Immunol, 11/25/2008

Measurement of phospholipid metabolism in intact neutrophils, Methods Mol Biol, 06/23/2008

Membrane targeting by APPL1 and APPL2: dynamic scaffolds that oligomerize and bind phosphoinositides, Traffic, 02/28/2008

Characterization of surface structure and p47phox SH3 domain-mediated conformational changes for human neutrophil flavocytochrome b, Biochemistry, 01/17/2008

Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR, FASEB J, 07/18/2007

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

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