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In 2006-2007, the Section on Rheumatology received external funding for basic and clinical research approaching $1.3 million. The research interests of the faculty are broad and include clinical research in interventional rheumatology such as arthroscopy, rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus (SLE), Sjogren's syndrome, and Raynaud's syndrome. |
Research Highlights
Research Studies Suggest Targeted Treatment Strategies for Lupus
Existing Drugs Show Promise for Treating End-Stage Renal Disease in Lupus
Two Drugs May Stabilize Plaques in Atherosclerosis
New Biomarkers for Lupus Found
Common Anti-seizure Drug Could Be Effective for Lupus Patients
Cancer Drug May Reduce Kidney Disease in Lupus
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Basic research studies of the faculty include molecular mechanisms of cellular immune dysfunction in SLE, signal transduction in B cells, and the control of macrophage functions in inflammation. The laboratory of Dr. Wallin has developed a system to study the molecular mechanisms of the anti-coagulant Coumadin and is currently isolating the Coumadin-sensitive enzyme present in the vitamin K cycle with a goal of creating better anticoagulant drugs and revealing the molecular cause of Coumadin resistance. |
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