Wake Forest University Baptist Medical Center
CareersFind a DoctorMake an AppointmentDepartmentsDirections & ParkingGiftsContact UsPRINT
 


Inflammatory Conditions or Diseases

Inflammation is a process where the body's white blood cells and chemicals help protect from infection and foreign substances such as bacteria and viruses.

In inflammatory diseases, the body's immune system triggers an inflammatory response when there are no foreign substances to fight off. In these autoimmune diseases, the body's normally protective immune system damages its own tissues. The body responds as if normal tissues are infected or are abnormal.

In an inflammatory response, chemicals are released into the blood or into affected tissues.  This release increases blood flow to the area, resulting in redness and warmth.  Some of the chemicals cause a leak of fluid into tissues, causing swelling.  An inflammatory response can stimulate nerves and cause pain, redness, joint stiffness and loss of joint function. 

Increased blood flow and the release of chemicals attract white blood cells to the inflamed area.  The increased white blood cells and inflammatory substances within joints can cause irritation and wearing down of cartilage and ultimate swelling of joint lining (synovium). 

Some types of arthritis are the result of misdirected inflammation. Some types of arthritis associated with inflammation include:

·         Rheumatoid arthritis

·         Tendonitis or bursitis

·         Gouty arthritis

·         Polymyalgia rheumatica

·         Systemic lupus erythematosus

·         Dermatomyositis and polymyositis -- inflammatory muscle diseases

 

Copyright: Wake Forest University School of Medicine and North Carolina Baptist Hospitals. All rights reserved.

Medical Center Boulevard

Winston-Salem, NC 27157

The information on this Website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified healthcare provider. If you have a medical problem or a health-related question, consult your physician or call Health On-Call at 336-716-2255 or 1-800-446-2255.

Send Feedback


Home

Site Index


Last Modified: 7/22/2008