Collaborations with Industry through the NIH Small Business
Innovative Research (SBIR) Grant Program
SBIR – Diabetes
Spectral analysis of laser Doppler fluxmetry signals indicates a difference in diabetic patients compared to non-diabetic patients with respect to the autonomic control of the cutaneous microcirculation of the feet. This SBIR, in conjunction with Transonic Systems, Inc. (Ithaca, NY), is supported by NIDDK and examines the feasibility of using this type of device for clinical applications.
SBIR – Millar
Hemodynamic measurement techniques in mice are being constantly refined in response to the needs of the scientific community. Collaborations with Millar, Inc. (Houston, TX), manufacturer of the world's best pressure measurement systems for clinical and basic research needs, were the basis for a funded SBIR proposal to create mouse-sized pressure sensing catheters with diameters of 300 microns. These devices are now in development and assessment of size and fidelity requirements are ongoing. In addition, ventricular pressure-volume techniques for mice are being further refined and used in this laboratory.