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Neurobiology and Anatomy

 

 

 

Ronald W. Oppenheim, Ph.D.
Professor
Washington University, St. Louis (1968)

Development of nervous system; programmed cell death; behavioral development; neurodegenerative disease; synaptogenesis; neural activity and brain development; history of neuroscience.


Selected Publications:

Kim WR, Kim Y, Eun B, Park O, Kim H, Kim K, Park C-H, Vinsant S, Oppenheim RW, and Sun W  2007  Impaired migration in the rostral migratory stream but spared olfactory function after the elimination of programmed cell death in Bax knock-out mice.  J Neuroscience 27(52): 14392-14403.

Oppenheim RW, Blomgren K, Ethell DW, Koike M, Komatsu M, Prevette D, Roth KA, Uchiyama Y, Vinsant S, and Zhu C  2008  Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-Independent, nonapoptotic pathway involving autophagy.  J Neuroscience 28(6):1490-1497.

 

Gould TW, Yonemura S, Oppenheim RW, Ohmori S, and Enomoto H  2008  The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes.  J Neuroscience 28(9):   2131-2146.

 

Jung A, Kim TW, Rhyu IJ, Kim H, Lee YD, Vinsant S, Oppenheim RW, and Sun W  2008  Misplacement of Purkinje cells during postnatal development in Bax knock-out mice:  A novel role for programmed cell death in the nervous system.  J Neuroscience 28(11):   2941-2948.

 

Oppenheim RW, Calderó J, Cuitat D, Esquerda J, McArdle JJ, Olivera BM, Prevette D, Teichert RW  2008  The rescue of developing avian motoneurons from programmed cell death by a selective inhibitor of the fetal muscle-specific nicotinic acetylcholine receptor.  Develop Neurobiol 68: 972-980.

 

Kim WR, Park O, Choi S, Choi S-Y, Park SK, Lee KJ, Rhyu IJ, Kim H, Lee YK, Kim HT, Oppenheim RW, and Sun W 2009 The maintenance of specific aspects of neuronal function and behavior is dependent on programmed cell death of adult-generated neurons in the dentate gyrus.  Eur J Neurosci 29: 1408-1421.

 


E-mail: roppenhm@wfubmc.edu