Ronald W. Oppenheim, Ph.D.
Professor
Washington University, St. Louis (1968)

Development of nervous system; programmed cell death; behavioraldevelopment; trophic factors and neurodegeneration; synaptogenesis; neuralactivity and brain development; history of neuroscience.

Selected Publications:

Oppenheim, Ronald W., David Prevette, Anselem D'Costa, Siwei Wang,Lucien J. Houenou and J. Michael McIntosh (2000) Reduction ofneuromuscular activity is required for the rescue of motoneurons fromnaturally occurring cell death by nicotinic-blocking agents. Journal ofNeuroscience 20(16):6117-6124.

Novak, Kristine D., David Prevette, Siwei Wang, Tom W. Gould andRonald W. Oppenheim (2000) Hepatocyte growth factor/scatter factor is aneurotrophic survival factor for lumbar but not for other somaticmotoneurons in the chick embryo. Journal of Neuroscience 20(1):326-337.

Oppenheim, Ronald W., Lucien J. Houenou, Alexander S. Parsadanian,David Prevette, William D. Snider and Liya Shen (2000) Glial cellline-derived neurotrophic factor and developing mammalian motoneurons:regulation of programmed cell death among motoneuorn subtypes. Journal ofNeuroscience 20(13):5001-5011.

Krieglstein, Kerstin, Sandra Richter, Lilla Farkas, Norbert Schuster,Nicole Dunker, Ronald W. Oppenheim and Klaus Unsicker (2000) Reduction ofendogenous transforming growth factors B prevents ontogenetic neuron death.Nature Neuroscience 3(11):1085-1090.

Oppenheim, Ronald W., Stefan Wiese, David Prevette, Mark Armanini, Siwei Wang, Lucien J. Houenou, Bettina Holtmann, Rudolf Gotz, Diane Pennica, and Michael Sendtner (2001) Cardiotrophin-1, a Muscle-Derived Cytokine, Is Required for the Survival of Subpopulations of Developing Motoneurons. Journal of Neuroscience 21(14):1283-1291.

E-mail: roppenhm@wfubmc.edu