Qiang Gu, Ph.D.

Assistant Professor

Office: (336) 716-9226
Lab: (336) 716-9701
Email: qgu@wfubmc.edu

Major projects in my laboratory involve using a high-throughput antibody microarray technique to determine differentially expressed protein levels. We have been optimizing and refining conditions and parameters for microarray applications, and have developed a novel approach for assessing the outcome accuracy of microarray experiments (Gu et al. 2007). We also have been utilizing this proteomics tool to investigate neurological disorders such as Alzheimer’s disease, epilepsy, and chronic alcoholics, as well as mammalian visual cortex during postnatal development. 

Selected recent publications

Gu Q, Sivanandam T, Haymore J (2007) Experimental approach for assessing the outcome accuracy of antibody microarray experiments. Journal of Proteome Research 6:4210-4217.

Gu Q (2007) Serotonin involvement in plasticity of the visual cortex. In: Monoaminergic Modulation of Cortical Excitability. Editors: Tseng K-Y and Atzori M, Springer, New York, pp113-124.

Gu Q, Sivanandam T, Kim AC (2006) Signal stability of Cy3 and Cy5 on antibody microarrays. Proteome Science 4:21.

Li P, Prasad SS, Mitchell DE, Hachisuka A, Sawada J-i, Al-Housseini AM, Gu Q (2006) Postnatal expression profile of OBCAM implies its involvement in visual cortex development and plasticity. Cerebral Cortex 16:291-299.

Yang B, Gu Q (2005) Contribution of glutamate-receptors to BDNF-induced elevation of intracellular Ca²⁺ levels. NeuroReport 16:977-980.

Gu Q (2003) Contribution of acetylcholine to visual cortex plasticity. Neurobiology of Learning and Memory 80:291-301.

Gu Q, Matsubara J, Boyd J (2003) Visual deprivation. In: Adler’s Physiology of the Eye, 10th Edition. Editors: Kaufman PL and Alm A. pp697-709. Mosby, St. Louis.

Gu Q (2002) Neuromodulatory transmitter systems in the cortex and their role in cortical plasticity. Neuroscience 111:815-835.