Reidar Wallin, PhD

Research Professor

Telephone: 716-6166
Fax: 716-9821                                                                                                             

Email: rwallin@wfubmc.edu

Education:  PhD, University of Oslo, Norway 1974

                  Dr.Philos, University of Tromso, Norway, 1980       

Current Research: Arterial Calcification, Vitamin K and vitamin K-dependent proteins.

Recent Publications:

1.      Wajih N, Hutson SM, Owen J, Wallin R. (2005) Increased production of functional recombinant human clotting factor IX by baby hamster kidney cells engineered to overexpress VKORC1, the vitamin K 2,3-epoxide–reducing enzyme of the vitamin K cycle. J Biol Chem 280: 31603-31607.

2.      Wajih N, Sane DC, Hutson SM, Wallin R. (2005) Engineering of a recombinant vitamin K-dependent gamma-carboxylation system with enhanced gamma-carboxyglutamic acid forming capacity: evidence for a functional CXXC redox center in the system. J Biol Chem 280: 10540-10547.

3.      Wajih N, Borras T, Xue W, Hutson SM, Wallin R. (2004) Processing and transport of matrix gamma-carboxyglutamic acid protein and bone morphogenetic protein-2 in cultured human vascular smooth muscle cells: evidence for an uptake mechanism for serum fetuin. J Biol Chem 279: 43052-43060.

4.      Wallin R, Hutson SM. (2004) Warfarin and the vitamin K-dependent gamma-carboxylation system. Trends Mol Med. 10: 299-302.

5.      Wajih N, Sane DC, Hutson SM, Wallin. (2004) The inhibitory effect of calumenin on the vitamin K-dependent gamma-carboxylation system. Characterization of the system in normal and warfarin-resistant rats. J Biol Chem 279: 25276-25283.    

Publications:
For a listing of additional publications, refer to PubMed, a service provided by the National Library of Medicine