Hang Shi, Ph.D

Assistant Professor, Section on Gerontology & Geriatric Medicine Department of Internal Medicine

Email: hshi@wfubmc.edu

Education:

Shanghai Medical University, Bachelor of Medicine, 1992

University of Tennessee at Knoxville, Ph.D., 2001

Beth Israel Deaconess Medical Center/Harvard Medical School, Postdoctoral Fellow, 2002-2007

Research Interests:

Molecular and cellular mechanism of obesity induced insulin resistance

Current Projects:

The inhibitory effects of tissue specific over-expression of SOCS3 on insulin and leptin signaling in the periphery and hypothalamus. AMPK regulation of inflammation in obesity and insulin resistance

Publications:

Koulmanda, M., Budo, E., Bonner-weir, S., Qipo, A., Putheti, P., Degauaque, N., Shi, H., Fan., Z., Flier, J. S., Auchincloss Jr., H., Zheng, X. X., Strom, T. B. Modification of adverse inflammation is required to cure new onset type I diabetic hosts. Proc. Natl. Acad. Sci. U.S.A. 104: 13074-13079, 2007.

Inoue, K. E., Shi, H., Howard, J. K., Daly, C. H., Lord, G. H., Rollins, B. J., Flier. J. S. Absence of CC chemokine ligand 2 does not limit macrophage infiltration into adipose tissue in obesity, and worsens obesity and metabolic function. Diabetes 56: 2242-2250, 2007.

Shi, H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest. 2006 Nov;116(11):3015-25.

Shi, H, Cave B, Inouye K, Bjorbaek C, Flier JS. Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance. Diabetes. 2006 Mar;55(3):699-707.

Publications:
For a listing of additional publications, refer to PubMed, a service provided by the National Library of Medicine