Thomas L. Smith, Ph.D.

Associate Professor, Orthopaedic Surgery

Associate, Molecular Medicine, Wake Forest Institute for Regenerative Medicine, Biomedical Engineering and Sciences and Physiology and Pharmacology

Email: tsmith@wfubmc.edu

Education:

Texas A&M University, B.S. (Zoology) -1971

Texas A&M University - College of Veterinary Medicine, M.S. (Physiology) - 1975

Wake Forest University - School of Medicine, Ph.D. (Physiology) - 1979

University of Mississippi Medical Center, Department of Physiology and Biophysics – Fellowship, 1979-1982

Research Interests:

Tissue Engineering in Orthopaedic Surgery

Control of the microcirculation

Hemodynamics and myocardial performance in mice and rats

Current Research:

Effects of exercise and PPARγ agonists on myocardial performance

Tissue engineered peripheral nerve conduits in mice

Regulation of neuromuscular function at the cellular level

Publications:

Whitlock PW, Smith TL, Poehling GG, Shilt JS, Van Dyke M. A naturally derived, cytocompatible, and architecturally optimized scaffold for tendon and ligament regeneration. Biomaterials. 2007 Jul 2.

Fosmire SP, Thomas R, Jubala CM, Wojcieszyn JW, Valli VE, Getzy DM, Smith TL, Gardner LA, Ritt MG, Bell JS, Freeman KP, Greenfield BE, Lana SE, Kisseberth WC, Helfand SC, Cutter GR, Breen M, Modiano JF. Inactivation of the p16 Cyclin-Dependent Kinase Inhibitor in High-Grade Canine Non-Hodgkin's T-Cell Lymphoma. Vet Pathol. 2007 Jul;44(4):467-78.

Stone AV, Ma J, Whitlock PW, Koman LA, Smith TL, Smith BP, Callahan MF. Effects of Botox(R) and Neuronox(R) on muscle force generation in mice. J Orthop Res. 2007 Jun 28.

Ma J, Shen J, Garrett JP, Lee CA, Li Z, Elsaidi GA, Ritting A, Hick J, Tan KH, Smith TL, Smith BP, Koman LA. Gene expression of myogenic regulatory factors, nicotinic acetylcholine receptor subunits, and GAP-43 in skeletal muscle following denervation in a rat model. J Orthop Res. 2007 Jun 13.

Gee L, Smith TL, Solomon M, Quinn MT, Lipton RB. The clinical, psychosocial, and socioeconomic concerns of urban youth living with diabetes. Public Health Nurs. 2007 Jul-Aug;24(4):318-28.

Publications:
For a listing of additional publications, refer to PubMed, a service provided by the National Library of Medicine