Jianfeng Xu, M.D., DrPH

Professor, Center for Human Genomics, Public Health Sciences-Epidemiology and Cancer Biology

Email: jxu@wfubmc.edu

Education:

Dr.Ph, 1997 Johns Hopkins
MPH, 1992 Johns Hopkins
MSc, 1987 School of Public Health, Shanghai Medical University, China
M.D., 1984 Shanghai Medical University, China

Research Interests:

Collaborating with other faculty members in the Center for Human Genomics, Dr. Xu has made important contributions in identifying the first prostate cancer susceptibility gene (HPC1), a prostate cancer susceptibility gene on the chromosome X (HPCX), and also an asthma susceptibility gene on chromosome 5. He is also an active member in the International Consortium of Prostate Cancer Genetics (ICPCG).

Dr. Xu's research group focuses on prostate cancer gene mapping using various approaches such as genetic linkage studies, family-based and population-based association studies, and molecular positional cloning technique. He has extensive experience in statistical genetic analysis, including genetic segregation analysis, linkage analysis, and association analysis. He oversees the analytical laboratory in the Center for Human Genomics, which is equipped with multiple SUN workstations that are specialized with various genetic software. The analytical laboratory is built to keep pace with the large volumes of data generated by the molecular laboratories. As a key to the analytical capacity of the Center for Human Genomics, Dr. Xu is also involved in several projects within the center for human genomics, such as osteoporosis, COPD, and cardiovascular diseases. Currently, his group consists of 8 faculty members, one genetic counselor, and several staff. This group has published six prostate cancer research papers and submitted 4 manuscripts, all to top publishers, in the year 2001 alone.

Recent Publications:

Malmberg KJ, Xu J. On the flexibility and the fallibility of associative memory. Mem Cognit. 2007 Apr;35(3):545-56.

Xu J, Malmberg KJ. Modeling the effects of verbal and nonverbal pair strength on associative recognition. Mem Cognit. 2007 Apr;35(3):526-44.

Xu J, Xu F, Hennebold JD, Molskness TA, Stouffer RL. Expression and Role of the CRH/Urocortin-Receptor-Binding Protein (CRH/UCN-R-BP) System in the Primate Corpus Luteum during the Menstrual Cycle. Endocrinology. 2007 Aug 9.

Zhang J, Diao B, Zhang N, Cui Z, Zhang L, Xu J, Kan B. Comparison of different electrophoretic parameters of Pulse-Field Gel Electrophoresis for Vibrio cholerae subtyping. J Microbiol Methods. 2007 Jul 13.

Yao ZX, Han Z, Xu J, Greeson J, Lecanu L, Papadopoulos V. 22R-Hydroxycholesterol induces differentiation of human NT2 precursor (Ntera2/D1 teratocarcinoma) cells. Neuroscience. 2007 Aug 2.

Publications:
For a listing of additional publications, refer to PubMed, a service provided by the National Library of Medicine