James A. MacKenzie, Ph.D.
Assistant Professor
Department of Biological Sciences
SUNY Oswego
Director, Molecular Biology and Biochemistry Center
SUNY Oswego College of Arts and Sciences
Email: jmackenz@oswego.edu
Education:
State University of New York at Fredonia, B.S., 1996
Research Interests:
Protein trafficking to mitochondria, environmental toxicants and cardiovascular reactivity in children.
Publications:
MacKenzie, J.A. and Payne, R.M. (2007) Mitochondrial Protein Import and Human Health and Disease. Biochimica et Biophysica Acta, 1772(5):509-523.
MacKenzie, J.A. and Payne, R.M. (2006) Preparation of Ribosomes Loaded with Truncated Nascent Proteins to Study Ribosome Binding to Mammalian Mitochondria. Mitochondrion, 6(2):67.
MacKenzie, J.A. and Payne, R.M. (2004) Ribosomes Specifically Bind to Mammalian Mitochondria via Protease-sensitive Proteins on the Outer Membrane. Journal of Biological Chemistry 279(11):9803.
Del Gaizo, V.B., MacKenzie, J.A., and Payne, R.M. (2003) Targeting Proteins to Mitochondria Using TAT. Molecular Genetics and Metabolism, 80(1-2):170.
Brunson, J.T., Engel, R.A., MacKenzie J.A., A. P. Nelson, Oaks, E. C., Ouellette, A.J.A., and Bio-Rad Laboratories. 2005-2007. Lab Manual for Biology 213. Ouellette, A.J.A. (editor). SUNY Oswego (published by the college bookstore for Oswego students).
Abstracts: (*Undergraduate or **Graduate Research Student)
Birdsall R.**, Bendinskas, K., and MacKenzie, J.A. (April 21, 2007) Comparative Analysis of Preparation Techniques for Proteomic Research. Presented at the Northeast Regional Undergraduate and Graduate Student Sigma Xi Poster Conference. (Poster Presentation, presented by R. Birdsall).
Sattelberg, P.*, MacKenzie, J.A., and Bendinskas, K. (November 4, 2006) Purification of Succinic Semialdehyde Reductase. Presented at the Sigma Xi Annual Meeting and Student Research Conference, Detroit, MI. (Poster Presentation, presented by P. Sattelberg).
Bendinskas, K., Chepko-Sade, B.D., and MacKenzie, J.A. (September 29, 2006) Learning by Doing: Chemistry-Biology Research as a Merck-AAAS Scholar. Presented at the Second Annual Oswego Symposium on Learning and Teaching, Oswego, NY. (Poster Presentation)
MacKenzie, J.A. and Payne, R.M. (April 5, 2006) Ribosome-Nascent Chain and Mitochondria Preparation to Study Ribosome-Mitochondria Interactions. Presented at Experimental Biology 2006, San Francisco, CA (Poster Presentation).
Payne, R.M. and MacKenzie J.A. (May 6, 2002) Evidence of a Novel Receptor Mediating Ribosome Binding to Mitochondria. Presented at 2002 Pediatric Academic Societies' Annual Meeting, Baltimore, MD. (Poster Presentation, presented by R.M. Payne) Pediatric Research 51(4):36A.
MacKenzie, J.A. and Payne, R.M. (April 22, 2002) Evidence of a Ribosome Receptor in Mammalian Mitochondria. Presented at Experimental Biology 2002, New Orleans, LA. (Poster Presentation) FASEB J. 16(4):A163.
MacKenzie, J.A. and Payne, R.M. (March 31 and April 2, 2001) A Novel Mechanism for Protein Targeting to Mammalian Mitochondria. Presented at Experimental Biology 2001, Orlando, FL. (Oral and Poster Presentation) FASEB J. 15(5):A881.
GRANTS:
NSF Major Research Instrumentation Grant
"Acquisition of an Ultracentrifuge for Research and Undergraduate Teaching"
PI: James A. MacKenzie; Co-PIs: Timothy Braun, Webe Kadima
Funding: $73,618 for 2007-2009
NIH Academic Research Enhancement Award Grant (R15)
“Lead and Vascular Reactivity to Acute Stress in Children”
PI: Brooks Gump, Co-PIs: James A. MacKenzie, Kestas Bendinskas
Funding: $205,741 for 2007-2009.
Merck/AAAS Undergraduate Science Research Program
PI: Kestas Bendinskas, Co-PI: James A. MacKenzie.
Funding: $60,000 for 2006-2009.
SUNY Oswego New Faculty Development Grant
PI: James A. MacKenzie.
Funding: $2,000 for 2005-2006.
UUP Professional Development Grant
PI: James A. MacKenzie.
Funding: $250 for 2005-2006.