Jasmina Varagic, M.D., Ph.D.
Research Assistant Professor, Hypertension and Vascular Research Center
Hanes Building, 6th Floor
Medical Center Boulevard
Winston-Salem, NC 27157
Tel: 336-716-2738
Fax: 336-716-2456
Email: jvaragic@wfubmc.edu
Education:
School of Medicine, University of Belgrade, Belgrade, Yugoslavia, MD, 1985
University of Belgrade, Belgrade, Yogoslavia, Master of Science in Biomedical Engineering, 1991
University of Belgrade Belgrade, Yugoslavia, Doctor of Philosophy in Pathophysiology 1997
Research Description:
Current Research:
Recent Publications:
Susic D, Varagic J, Ahn J, Matavelli, LC, Frohlich ED. Long-term mineralocorticoid receptor blockade reduces fibrosis and improves cardiac performance and coronary hemodynamics in elderly SHR. Am J Physiol Heart Circ Physiol 2006 Aug 11 (in press).
Matavelli LC, Zhou X, Varagic J, Susic D, Frohlich ED. Salt-loading produces severe renal hemodynamic dysfunction independent of arterial pressure in spontaneously hypertensive rats.
Am J Physiol Heart Circ Physiol 2006 Sep 22 (in press).
Varagic J, Frohlich ED, Diez J, Susic D, Ahn J, Lopez B, Sanchez A. Myocardial fibrosis, impaired coronary hemodynamics, and biventricular dysfunction in salt-loaded SHR. Am J PhysiolHeart Circ Physiol 2006 Apr;290(4):H1503-H1509.
Susic, D, Varagic J, Ahn J, Matavelli LC, Frohlich ED. Beneficial cardiovascular actions of eplerenone in the spontaneously hypertensive rat. J Cardiovasc Pharmacol Ther 2005 Sep;10(3):197-203.
Slama M, Ahn J, Peltier M, Maizel J, Chemla D, Varagic J, Susic D, Tribouilloy C, Frohlich ED. Validation of echocardiographic and Doppler indexes of left ventricular relaxation in adult hypertensive and normotensive rats. Am J Physiol 2005 289:H1131-H1136.
Frohlich ED, Varagic J. Sodium directly impairs target organ function in hypertension. Curr Opin Cardiol 2005 Sep;20(5):424-429.
Varagic J, Frohlich ED. Hypertension and the multifactorial role of salt. Laboratory Medicine 2005;36:2-5.
Frohlich ED, Varagic J. The role of sodium in hypertension is more complex than simply elevating arterial pressure. Nat Clin Pract Cardiovas Med 2004 Nov;1(1):24-30.
Ahn J, Varagic J, Slama M, Susic D, Frohlich ED. Cardiac structural and functional responses to salt loading in SHR. Am J Physilo Heart Circ Physiol 2004 Aug;287:H767-H772.
Susie D, Varagic J, Ahn J, Frohlich ED. Crosslink breakers: a new approach to cardiovascular therapy. Curr Opin CCardiol. 2004 Jul;19(4):336-340.
Susic D, Varagic J, Ahn Jwari, Frohlich ED. Cardiovascular and renal effects of a collagen cross-ling breaker (ALT 711) in adult and aged spontaneously hypertensive rats. Am J Hypertens 2004 Apr;17(4):328-333.
Susic D, Varagic J, Ahn J, Frohlich ED. Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes and hypertension. Curr Drug Targets-Cardiovasc Hematol Disord 2004 Mar;4(1);97-101.
Varagic J, Susic D, Slama M, Ahn J, Frohlich ED. High dietary salt intake: Left ventricular hypertrophy and fibrosis. Israeli Bilingual Journal of Hypertension 2004;3:21-25.