1.      Process

Use of aniline or one of its homolog compounds in a laboratory environment.

2.      Physical Hazards

q       Colorless to brown, oily liquid with an aromatic amine-like odor. (Note: A solid below 21°F.)

q       Class IIIA Combustible Liquid: Flash Point is about 158°F.

q       Incompatibilities and Reactivities: alkalis, strong oxidizers, strong acids, and toluene diisocyanate.

3.      Health Hazards

q       Aniline and its related compounds can be toxic via inhalation, skin absorption, ingestion, skin and/or eye contact.

q       Symptoms of overexposure include:

●         Headache.

●         Weakness.

●         Dizziness.

●         Cyanosis.

●         Ataxia.

●         Dyspnea (breathing difficulty) on effort.

●         Tachycardia.

●         Irritation of the eyes.

●         Methemoglobinemia.

●         Cirrhosis.

q       Aniline is a potential occupational carcinogen.

4.      Personal Protective Equipment

q       EYE PROTECTION

·          Safety glasses, goggles or face shields shall be worn during operations in which might contact the eyes (e.g., through vapors or splashes of solution).

·          Ordinary (street) prescription glasses do not provide adequate protection.  Adequate safety glasses must meet the requirements of the Practice for Occupational Education Eye and Face Protection (ANSI Z87.1-1989) and must be equipped with side shields. 

·          Fisherbrand® Chemical Splash Goggles, catalog # 19-041-739 are recommended.

·          Contact lenses shall not be worn if the potential exist for aniline and homolog’s exposure.

q       HAND PROTECTION

·          Use of Nitrile gloves are recommended when using aniline and homolog compounds and are available through Lab Safety Supply catalogue # 2BD-1414655.

q       LAB COATS, ETC.

·          Lab coats, close toed shoes and long sleeved clothing shall be worn when handling aniline compounds. Protective clothing shall be worn to prevent any possibility of skin contact with aniline compounds.

q       SAFETY SHOWER/EYEWASH 

·          Where the eyes or body of any person may be exposed to aniline and homologs, suitable facilities for quick drench or flushing of the eyes and body shall be provided within the work area for immediate emergency use. 

·          Bottle type eyewash stations are not acceptable.

5.      Designated Area for Use and Containment Devices

q       All aniline compounds work shall be done in the laboratory fume hood.

q       The fume hood’s sash must be in the position where a face velocity of 100 feet per minute is achieved.  

q       Mark fume hood and other use areas a designated area for use of carcinogens.

6.      Special Handling Procedures and Storage Requirements

Spill-X-S kit, which is available from Lab Safety Supply, catalogue # 2BD-14628, must be available in the event of a liquid spill less than 300 cc.

7.      Waste Disposal

Excess aniline and all waste material containing aniline must be placed in an unbreakable secondary container labeled with the following "HAZARDOUS WASTE ANILINE ". Full containers of aniline waste must be disposed of according to WFUHS EH&S Hazardous Waste Program.

8.      Decontamination of Equipment and Area

Contact WFUHS EH&S at 716-1221 for decontamination information.

9.      Spill and Accident Procedures

In the event of a liquid spill greater than 300 cc, immediately vacate and secure the area. Contact WFUBMC Security at 716-9111.