1. Process Use of the following amine compounds in a laboratory environment: q Butylamine q Diisopropylamine q Ethanolamine q Isopropylamine 2. Physical hazards q Colorless liquid with a fishy, ammonia-like odor. q Ethanolamine may be a solid below 51°F. q Isopropylamine may be a gas above 91°F. q Flammable · Butylamine, Diisopropylamine, and Isopropylamine have flashpoint less 20 F. · Ethanolamine has a flashpoint of 186°F. q Incompatibilities and Reactivities: amines react with a variety of materials including aldehydes, epoxides, ketones, iron, strong acids and strong oxidizers. · Ethanolamine may attack copper, brass, and rubber, reacts violently with Acrolein, Acrylonitrile, Epichlorohydrin, Beta-Propiolactone and Vinyl Acetate. · Butylamine may corrode some metals in presence of water. · Diisopropylamine and Isopropylamine – strong oxidizing agents. 3. Health Hazards q Corrosive. q Routes of exposure for these materials include inhalation, ingestion, skin and/or eye contact, and skin absorption. q Effect of overexposure include: · Irritation of the eyes, skin, nose, throat, respiratory system. · Lethargy (drowsiness or indifference). · Headache. · Skin flush and dermatitis. · Eye and skin burns. · Nausea, vomiting. · Visual disturbance. · Pulmonary edema. · Visual disturbance. q Target Organs: eyes. 4. Personal Protective Equipment q EYE PROTECTION · Safety glasses, goggles or face shields shall be worn during operations in which might contact the eyes (e.g., through vapors or splashes of solution). · Ordinary (street) prescription glasses do not provide adequate protection. Adequate safety glasses must meet the requirements of the Practice for Occupational Education Eye and Face Protection (ANSI Z87.1-1989) and must be equipped with side shields. · Fisherbrand® Chemical Splash Goggles, catalog # 19-041-739 are recommended. · Contact lenses should not be worn if the potential exist for amine compounds exposure. q HAND PROTECTION · Use of Nitrile gloves are recommended when using Amine Compounds and are available through Lab Safety Supply catalogue # 2BD-1414655. q LAB COATS, ETC. · Lab coats, close toed shoes and long sleeved clothing shall be worn when handling amine compounds. Protective clothing shall be worn to prevent any possibility of skin contact with amine compounds. q SAFETY SHOWER/EYEWASH · Where the eyes or body of any person may be exposed to amine compounds, suitable facilities for quick drench or flushing of the eyes and body shall be provided within the work area for immediate emergency use. · Bottle type eyewash stations are not acceptable. 5. Designated Area for Use and Containment Devices q All amine compounds work shall be done in the laboratory fume hood. q The fume hood’s sash must be in the position where a face velocity of 100 feet per minute is achieved. 6. Special Handling Procedures and Storage Requirements q Keep Tightly Closed q Hygroscopic q Store In A Cool Dry Place q Spill-X-S Kit, which is available through Lab Safety Supply, catalog #2BD-14628, must be available in the event of a liquid spill less than 300 cc. 7. Waste Disposal Excess amine compounds and all waste material containing amine compounds must be placed in an unbreakable secondary container labeled with the following "HAZARDOUS WASTE AMINE COMPOUNDS ". Full containers of amine compounds waste must be disposed of according to WFUHS EH&S Hazardous Waste Program. 8. Decontamination of Equipment and Area Contact WFUHS EH&S at 716-1221 for decontamination information. 9. Spill and Accident Procedures q In the event of a liquid spill greater than 300 cc, immediately vacate and secure area and contact WFUBMC Security at 716-9111. |